在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Vesicular acetylcholine transporter (Slc18a3), partial

  • 中文名稱:
    大鼠Slc18a3重組蛋白
  • 貨號:
    CSB-YP720309RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Slc18a3重組蛋白
  • 貨號:
    CSB-EP720309RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Slc18a3重組蛋白
  • 貨號:
    CSB-EP720309RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Slc18a3重組蛋白
  • 貨號:
    CSB-BP720309RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Slc18a3重組蛋白
  • 貨號:
    CSB-MP720309RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Slc18a3; Vacht; Vat; Vesicular acetylcholine transporter; VAChT; rVAT; Solute carrier family 18 member 3
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in acetylcholine transport into synaptic vesicles.
  • 基因功能參考文獻:
    1. VACHT is inserted into the presynaptic membrane during synaptic vesicles' exocytosis, removed during their endocytotic recycling, and plays a role in non-quantal secretion of acetylcholine. PMID: 21557989
    2. VAChT was primarily localized to membranes of small synaptic vesicles in axon terminals PMID: 11304756
    3. VAChT interacts with clathrin-associated adaptor complexes AP-1 and AP-2 PMID: 14724281
    4. Semi-quantitative ultrastructural analysis reveals that from 5% to 13% of VAChT-immunoreactive presynaptic profiles contained mu opioid receptor (MOR). Additionally, 7% of VAChT presynaptic profiles directly apposed MOR axons and terminals. PMID: 15306235
    5. This study locates the acetylcholine (ACh) binding site in the vesicular acetylcholine transporter (VAChT) and identifies the amino acid residues linked to the individual binding and rates of the transmembrane reorientation steps of a transport cycle. PMID: 15366926
    6. A model for VAChT is suggested in which the known ion pair between lysine in transmembrane domain(TMD)II and aspartate in TMDXI controls the conformation or relative position of TMDXI, which in turn controls additional TMDs in the VAChT carboxy-terminal. PMID: 15924414
    7. During VAChT trafficking, the C-terminal dileucine-containing motif is sufficient as a dual signal for both internalization and synaptic vesicle targeting. PMID: 17451554
    8. 18.0 mg/kg dose of chlorpyrifos was associated with (brain region-dependent) decreases in nerve growth factor receptors and cholinergic proteins including the vesicular acetylcholine transporter PMID: 17548533
    9. These results made [125I]-( R,R)-5-AOIBV inferior to [125I]-IBVM for the VAChT exploration in vivo. PMID: 17998100
    10. VAChT concentrations were increased in the brain of control SHR compared to age-matched normotensive Wistar-Kyoto rats. PMID: 19021024
    11. Sympathetic preganlionics segregate mENK from VAChT and ChAT; most of the subset of mENKergic varicosities negative for VAChT also do not express Syn, suggesting a different vesicular pattern in these sympathetic preganglionic varicosities. PMID: 19524025

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Major facilitator superfamily, Vesicular transporter family
  • 組織特異性:
    High expression in all major cholinergic cell groups, including peripheral postganglionic parasympathetic cells, preganglionic sympathetic and parasympathetic cells, ventral spinal cord and brainstem motoneurons, cell groups in the basal forebrain, the ha
  • 數據庫鏈接:

    KEGG: rno:60422

    UniGene: Rn.9987



主站蜘蛛池模板: 免费精品国偷自产在线2020| 狂野av人人澡人人添| 超碰cao已满18进入离开官网| 亚洲高清乱码午夜电影网制服| 久久99热久久99精品| 久久久久久九九99精品 | 国产又粗又硬又大爽黄老大爷视频| 国产情侣真实露脸在线| 亚洲女教师丝祙在线播放| 国语对白嫖老妇胖老太| 亚洲精品国偷拍自产在线观看蜜桃 | 精品成人av一区二区三区| 无码中文av有码中文av| 国内熟妇人妻色在线视频| 性色av一区二区三区咪爱四虎| 男人扒开女人腿桶到爽免费| 国产精品美女www爽爽爽视频| 麻豆成人久久精品二区三区免费| 亚洲国产无套无码av电影| 欧美日韩在线视频| 久久精品国产精品亚洲下载| 成年女人片免费视频播放a| 国产一区二区三区在线观看免费| 天堂网在线最新版www资源网| 亚洲一区无码中文字幕| 久久久97丨国产人妻熟女| 青青草97国产精品免费观看| 亚洲综合激情另类小说区| 中文字幕精品亚洲无线码vr| 国产亚洲美女精品久久久2020 | 亚洲人成无码网www电影麻豆| 亚洲精品无码伊人久久| 熟女视频一区二区在线观看| 亚洲欧美日本韩国| 2020年国产精品| 玩弄丰满少妇xxxxx性多毛| 日本午夜免费福利视频| 香蕉噜噜噜噜私人影院| 久久麻豆成人精品av| 丰满少妇被猛烈进入高清播放| 国产黄在线观看免费观看不卡|