在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Vasopressin V2 receptor (Avpr2), partial

Recombinant Rat Vasopressin V2 receptor (Avpr2), partial

  • 中文名稱：
    Recombinant Rat Vasopressin V2 receptor(Avpr2),partial
  • 貨號：
    CSB-YP002470RA1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat Vasopressin V2 receptor(Avpr2),partial
  • 貨號：
    CSB-EP002470RA1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat Vasopressin V2 receptor(Avpr2),partial
  • 貨號：
    CSB-EP002470RA1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat Vasopressin V2 receptor(Avpr2),partial
  • 貨號：
    CSB-BP002470RA1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat Vasopressin V2 receptor(Avpr2),partial
  • 貨號：
    CSB-MP002470RA1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Avpr2; Vasopressin V2 receptor; V2R; AVPR V2; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptor
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.
  • 基因功能參考文獻：
    1. Chronic vasopressin V2R antagonism may contribute to the worsening of PAH and the development of RV remodeling. PMID: 26924211
    2. Regulation of V2 receptor by vasopressin PMID: 26335823
    3. Data suggest that vasopressin receptors V1b (Avpr1b) and V2 (Avpr2) in neurons of cerebral ventricles mediate stress-induced baroreflex desensitization enabling concurrent hypertension and tachycardia. PMID: 23488898
    4. the presence of an increased AVP sensitivity in the CDs from CHF rats, associated with an acquired recycling ability of the V2 receptor PMID: 24089411
    5. There was no change in V receptor expression during the development of hypertension. PMID: 23246465
    6. V2 receptors in the alveolar epithelium of adult rat regulate alveolar fluid clearance. PMID: 22700868
    7. role of beta-arrestins downstream of a transactivation event is not limited to the V2R, because we observed a similar involvement for an unrelated GPCR (the platelet-activating factor receptor) indicating that it may be a general mechanism shared among GPCRs PMID: 22493236
    8. Chronic treatment with V2 receptor antagonist tolvaptan prevents the progression of left ventricular dysfunction and renal injury in hypertensive rats with heart failure. PMID: 22628529
    9. The receptor expression in accessory olfactory bulb neurons is independent of the interaction with AOB neurons in the early developmental stage, but is maintained by the active interaction with accessory olfactory bulb neurons. PMID: 21679749
    10. Confocal microscopy of isolated inner medullary collecting duct tubules showed that the V2R is expressed both intracellularly and in basolateral membrane domains. PMID: 17553938
    11. Female rats express significantly more vasopressin V2 receptor mRNA and protein in kidneys than males, resulting in a greater sensitivity to vasopressin V2 receptor agonists. PMID: 21123493
    12. Localized aquaporins and vasopressin type 2 receptor (V2-R) in the stria vascularis to evaluate the role of the AQP water channel system in water homeostasis of the SV. PMID: 19796672
    13. chronic stimulation of vasopressin V2 receptor raises basal blood pressure in rats and exacerbates the development of DOCA-salt hypertension, organ damage, and mortality PMID: 12072411
    14. Increased amounts of renal medulla V2 receptors in spontaneously hypertensive rats play an important role in the pathophysiology of hypertension. PMID: 12566855
    15. These results suggest that arginine-vasopressin (AVP) induces the translocation of placental leucine aminopeptidase (P-LAP) via V2 vasopressin receptors, and that P-LAP plays a role in the regulation of AVP levels in the renal collecting duct. PMID: 12709058
    16. The inflammatory response to acute endotoxemia down regulates V2 VP receptors and aquaporin-2 of the kidney inner medulla resulting in prolonged impairment of the renal capacity to concentrate urine. PMID: 14675036
    17. functional impairment of renal concentrating ability in aged rats that is not due to impaired secretion of AVP but appears to be related to impaired responsiveness to AVP that is secondary to a downregulation of renal V2R expression and AQP2 abundance. PMID: 15213068
    18. V2 vasopressin receptor has a role in inhibiting signaling through its interaction with receptor dimer and G protein PMID: 15452133
    19. Reduced expression of aquaporin-2 and V(2)-receptor led to impairment of concentration capacity in the kidneys and decrease in urine osmolarity in acute inflammation. PMID: 15723124
    20. Expression of V(2)R is first detectable in the late embryonic stage of rat ontogeny starting from day E18 and gradually increasing with kidney maturation and in the adult, V(2)R is differentially distributed in the various nephron segments. PMID: 16014025
    21. these data suggest that increased production of PGE(2) in renal medulla plays a key role in the downregulation of V2 receptor in dehydration. PMID: 17190913
    22. V(2)R mRNA was expressed in medullary TAL (MTAL), macula densa, connecting tubule, and cortical and medullary collecting duct, and was weakly expressed in cortical TAL and distal convoluted tubule in rat, mouse, and human PMID: 17626156
    23. Angiotensin II regulates the V2 receptor complex and pS256-AQP2 in postobstructive kidney inner medulla, probably by stimulating cAMP generation. PMID: 18971210
    24. demonstrate the postnatal expression of V(2a) and V(2b) variants in the rat cerebellum PMID: 19281786
    25. The authors observed that binding of gC1qR to the full-length receptor modifies the intrinsic tryptophan fluorescence binding curves of V2 to an antagonist. PMID: 19285506
    26. Describe VRQ397 (CRAVKY), a potent noncompetitive antagonist of V2R, which exhibits functional selectivity, in line with properties of a negative allosteric modulator. PMID: 19641130

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily
  • 組織特異性：
    Kidney.
  • 數據庫鏈接：


主站蜘蛛池模板： 国产a三级久久精品| 久久婷婷人人澡人人爽人人爱 | 337p粉嫩大胆色噜噜噜| 国产69精品久久久久久久 | 少妇和邻居做不戴套视频| 亚洲另类激情专区小说| 日韩大片高清播放器| 未满十八18禁止免费无码网站| 亚洲欧洲日产韩国在线看片| 成人免费精品网站在线观看影片| 在线欧美中文字幕农村电影| 日韩激情无码免费毛片| 亚洲美女高清无水av| 在线观看片免费人成视频无码| 午夜精品一区二区三区在线观看| 自拍日韩亚洲一区在线| 秋霞最新高清无码鲁丝片| 中国老妇xxxx性开放| 福利cosplayh裸体の福利| 国产av人人夜夜澡人人爽| 狠狠亚洲色一日本高清色| 亚洲精品久久一区二区三区四区| h人成在线看免费视频| 日本乱偷人妻中文字幕| 大伊香蕉精品视频在线天堂| 国产成人乱色伦区| 国产三级精品三级在线专区| 久久久久国产精品嫩草影院| 国产精品亚洲综合一区在线观看 | 黑人巨大精品欧美| 久久精品中文无码资源站| 亚洲乱码日产精品bd在| 国产又黄又爽又色的免费视频| 亚洲乱码日产精品bd在线观看| 亚洲性无码一区二区三区| 日本一卡二卡3卡四卡网站精品| 国产三级av在线播放| 久久久精品区二区三区免费| 97se亚洲国产综合自在线| 久久精品www人人爽人人| 好男人社区神马在线观看www|