在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Sorting nexin-27 (Snx27)

Recombinant Rat Sorting nexin-27 (Snx27)

  • 中文名稱：
    大鼠Snx27重組蛋白
  • 貨號(hào)：
    CSB-YP813008RA
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Snx27重組蛋白
  • 貨號(hào)：
    CSB-EP813008RA
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Snx27重組蛋白
  • 貨號(hào)：
    CSB-EP813008RA-B
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Snx27重組蛋白
  • 貨號(hào)：
    CSB-BP813008RA
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Snx27重組蛋白
  • 貨號(hào)：
    CSB-MP813008RA
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Snx27
  • Uniprot No.：
  • 別名：
    Snx27; Mrt1; Sorting nexin-27; MAP-responsive gene protein; Methamphetamine-responsive transcript 1 protein; PDZ-protein Mrt1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-539
  • 氨基酸序列
    MADEDGEGIH PSTPHRNGGG GGGSGLHCAG NGGGGGGGPR VVRIVKSESG YGFNVRGQVS EGGQLRSING ELYAPLQHVS AVLPGGAADR AGVRKGDRIL EVNGVNVEGA THKQVVDLIR AGEKELILTV LSVPPHEADN LDPSDDSLGQ SFYDYTEKQA VPISVPTYKH VEQNGEKFVV YNVYMAGRQL CSKRYREFAI LHQNLKREFA NFTFPRLPGK WPFSLSEQQL DARRRGLEEY LEKVCSIRVI GESDIMQEFL SESDENYNGV SDVELRVALP DGATVTVRVK KNSTTDQVYQ AIAAKVGMDS TTVNYFALFE VINHSFVRKL APNEFPHKLY VQNYTSAVPG TCLTIRKWLF TTEEEVLLND NDLAVTYFFH QAVDDVKKGY IKAEEKSYQL QKLYEQRKMV MYLNMLRTCE GYNEIIFPHC ACDSRRKGHV ITAISITHFK LHACTEEGQL ENQVIAFEWD EMQRWDTDEE GMAFCFEYAR GEKKPRWVKI FTPYFNYMHE CFERVFCELK WRKENIFQMA RSQQRDVAT
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate (PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.
  • 基因功能參考文獻(xiàn)：
    1. SNX27 is required for the exocytosis of NHE3 from early endosome to plasma membrane and the regulation of the retention of NHE3 on the plasma membrane. PMID: 25851603
    2. The regulation of the VPS26A-SNX27 interaction modifies mGluR5 trafficking which mediates neuropathic pain. PMID: 26538661
    3. SNX27 is synaptically enriched and its level of expression regulates targeting of AMPARs to the neuronal surface. Loss of SNX27 abolishes recruitment of surface AMPARs during chemical LTP. PMID: 25071192
    4. Gene is developmentally regulated and stimulated by methamphetamine in the neocortex. PMID: 12740601
    5. These findings suggest the differential regulation by stimulant of neocortical mrt1 expression and supports the view that stimulant induction of mrt1 may be involved in the early molecular signalings for stimulant sensitization. PMID: 12774298
    6. SNX27 promotes the endosomal movement of Kir3 (GIRK) channels, leading to reduced surface expression, increased degradation and smaller Kir3 potassium currents. PMID: 17828261

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Early endosome membrane; Peripheral membrane protein. Cytoplasm, cytosol.
  • 組織特異性：
    Isoform 1 is predominantly expressed in the testis, whereas isoform 2 is predominant in various brain regions, including, neocortex, paleocortex, striatum, hippocampus, cerebellum and brain stem. Expressed in cells of hematopoietic origin.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： av片在线播放| 国产精品乱码在线观看| 国产精品亚洲а∨无码播放| 国产精品久久综合免费| 久久久久人妻精品区一三寸| 国产在线精品一区二区三区| 动漫av网站免费观看| 久久久国产精华液| 国产成人亚洲精品无码最新| 天堂中文在线最新版地址 | 欧美人与禽zoz0性伦交| 春药玩弄少妇高潮吼叫| 亚洲日本va在线视频观看| 无码午夜人妻一区二区三区不卡视频| 中国浓毛少妇毛茸茸| 国产福利在线视频蜜芽tv| 一区二区视频日韩免费| 国产精品久久久久久久久绿色 | 18禁女裸乳扒开免费视频| 四虎亚洲精品无码| 深爱婷婷国产在线精品av| 亚洲另类激情综合偷自拍图| 亚洲色欲一区二区三区在线观看| 国产美女视频免费观看的网站| 国内精品久久久久久久电影视| 久久精品国产99精品国产亚洲性色| 亚洲欧美日韩国产成人| 久久综合97丁香色香蕉| 肉体裸交137日本大胆摄影| 久久综合亚洲色一区二区三区| 国产午夜福利在线观看红一片| 国产成人无码a区在线| 无码视频免费一区二区三区| 欧美性猛交ⅹxxx乱大交妖精| 国产伦精品一区二区三区妓女下载| 婷婷俺也去俺也去官网| 亚洲精品av无码喷奶水网站| 45分钟免费真人视频| 成年片色大黄全免费软件到 | 亚洲欧美日韩中文在线制服| 非洲人与性动交ccoo|