在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Sodium/potassium-transporting ATPase subunit alpha-2 (Atp1a2), partial

Recombinant Rat Sodium/potassium-transporting ATPase subunit alpha-2 (Atp1a2), partial

  • 中文名稱：
    Recombinant Rat Sodium/potassium-transporting ATPase subunit alpha-2(Atp1a2) ,partial
  • 貨號：
    CSB-YP002323RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat Sodium/potassium-transporting ATPase subunit alpha-2(Atp1a2) ,partial
  • 貨號：
    CSB-EP002323RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat Sodium/potassium-transporting ATPase subunit alpha-2(Atp1a2) ,partial
  • 貨號：
    CSB-EP002323RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat Sodium/potassium-transporting ATPase subunit alpha-2(Atp1a2) ,partial
  • 貨號：
    CSB-BP002323RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat Sodium/potassium-transporting ATPase subunit alpha-2(Atp1a2) ,partial
  • 貨號：
    CSB-MP002323RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Atp1a2Sodium/potassium-transporting ATPase subunit alpha-2; Na(+)/K(+) ATPase alpha-2 subunit; EC 7.2.2.13; Na(+)/K(+) ATPase alpha(+) subunit; Sodium pump subunit alpha-2
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
  • 基因功能參考文獻：
    1. cardiomyocyte ATP1A2 is a target of A/R injury PMID: 29394489
    2. Hypoxia reduces smooth muscle cell expression of Atp1a2 which may contribute to basilar artery vasoconstriction. PMID: 26924456
    3. Data suggest that, in polycystic ovary syndrome, heart exhibits alteration in processing of Atp1a2 (Na+/K+ transporting ATPase alpha 2) with decreases in plasma membrane content of this enzyme subunit. PMID: 25988879
    4. Na-K-ATPase alpha2 does not regulate Src. PMID: 26108663
    5. Na,K-ATPase alterations precede hindlimb suspension-induced muscle atrophy. PMID: 25654120
    6. Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease PMID: 24356962
    7. Results suggest that the increase in the Na(+)/water ratio and a reduction in ATP1alpha2 may be associated with cerebral aneurysm formation. PMID: 23045463
    8. The nicotinic acetylcholine receptor and the Na,K-ATPase alpha2 isoform interact to regulate membrane electrogenesis in skeletal muscle. PMID: 20595385
    9. The Na+K+ ATPase alpha 2 subunit is localized in astrocytic processes around axonal or dendritic elements of glutamatergic axo-dendritic synaptic junctions in the frontoparietal somatosensory cortex. PMID: 11950769
    10. Structural basis for alpha1 versus alpha2 isoform-distinct behavior of the Na,K-ATPase PMID: 12529322
    11. beta(1)-Na(+),K(+)-ATPase is likely to represent the most physiologic and efficient subunit for HKalpha(2) assembly in distal colon. PMID: 15327400
    12. missense mutants R689Q and M731T have reduced catalytic turnover and increased apparent affinity for extracellular K(+) PMID: 16037212
    13. cyclic stretch mainly stimulated translocation of alpha2-subunit of Na+-K+-ATPase from endosomes to the plasma membrane via a PI 3-kinase-dependent mechanism in cultured skeletal muscle cells in vitro, which in turn increased the activity of the Na pump. PMID: 16893515
    14. The functional density of NKA-alpha2 is approximately 4.5 times higher in the T-tubules vs. external sarcolemma in ventricular cardiomyocytes. PMID: 17392375
    15. Downregulation of Atp1a2 attenuated control of Na/Ca exchanger activity in heart failure, reducing its capability to extrude Ca2+ from cardiomyocytes. PMID: 18203708
    16. Protein and mRNA levels for Na(+)-K(+)-ATPase alpha2 isoform were decreased in failing hearts. This was prevented by analapril or losartan. PMID: 18418421
    17. Analysis of exercise-induced Na+-K+ exchange in rat skeletal muscle in vivo. PMID: 18586859
    18. Disturbances in skeletal muscle Na(+)-K(+)-ATPase regulation, particularly the alpha(2)-subunit, may contribute to impaired ion homeostasis in insulin-resistant states such as obesity and type 2 diabetes. PMID: 19366873

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Cation transport ATPase (P-type) (TC 3.A.3) family, Type IIC subfamily
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲乱亚洲乱妇无码麻豆| 亚洲日韩av一区二区三区中文 | 老色鬼永久精品网站| 欧美人与动牲交a欧美精品| 97国产精品麻豆性色aⅴ人妻波 | 亚洲精品国产一区二区精华| 影音先锋无码a∨男人资源站| 嫩草欧美曰韩国产大片| 99热这里只有精品免费播放| 中文字幕日韩精品无码内射| a∨变态另类天堂无码专区| 先锋影音人妻啪啪va资源网站| 日产精品久久久久久久| 国产精品久久无码一区二区三区网| 亚洲高清无在码在线电影| 国产亚洲精品自在久久蜜tv| 国产成人无码一二三区视频| 女人和拘做爰正片视频| 男女同房做爰爽免费| 亚洲国产精品成人影片久久| 国产内射爽爽大片| 国产又爽又猛又粗的视频a片| 久久精品国产9久久综合| 亚洲中国最大av网站| 精品少妇一区二区三区免费观| 亚洲精品成人片在线播放| 亚洲欧洲日产最新| 先锋影音av最新资源| 久久精品中文字幕一区| 丝袜老师办公室里做好紧好爽| 丰满人妻被公侵犯完整版| 无码国内精品久久综合88| 色播久久人人爽人人爽人人片av| 亚洲色大成网站在线| 国产成人麻豆亚洲综合精品| 国产精品美女久久久久久久久| 欧美成人看片一区二区| 国产成人亚洲综合图区| 人妻少妇精品一区二区三区| r级无码视频在线观看| 五月激激激综合网亚洲|