在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Serine/threonine-protein kinase D2 (Prkd2), partial

  • 中文名稱:
    大鼠Prkd2重組蛋白
  • 貨號:
    CSB-YP726380RA
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Prkd2重組蛋白
  • 貨號:
    CSB-EP726380RA
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Prkd2重組蛋白
  • 貨號:
    CSB-EP726380RA-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Prkd2重組蛋白
  • 貨號:
    CSB-BP726380RA
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Prkd2重組蛋白
  • 貨號:
    CSB-MP726380RA
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Prkd2Serine/threonine-protein kinase D2; EC 2.7.11.13; nPKC-D2
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress-induced NF-kappa-B activation, inhibition of HDAC7 transcriptional repression, signaling downstream of T-cell antigen receptor (TCR) and cytokine production, and plays a role in Golgi membrane trafficking, angiogenesis, secretory granule release and cell adhesion. May potentiate mitogenesis induced by the neuropeptide bombesin by mediating an increase in the duration of MAPK1/3 (ERK1/2) signaling, which leads to accumulation of immediate-early gene products including FOS that stimulate cell cycle progression. In response to oxidative stress, is phosphorylated at Tyr-438 and Tyr-718 by ABL1, which leads to the activation of PRKD2 without increasing its catalytic activity, and mediates activation of NF-kappa-B. In response to the activation of the gastrin receptor CCKBR, is phosphorylated at Ser-244 by CSNK1D and CSNK1E, translocates to the nucleus, phosphorylates HDAC7, leading to nuclear export of HDAC7 and inhibition of HDAC7 transcriptional repression of NR4A1/NUR77. Upon TCR stimulation, is activated independently of ZAP70, translocates from the cytoplasm to the nucleus and is required for interleukin-2 (IL2) promoter up-regulation. During adaptive immune responses, is required in peripheral T-lymphocytes for the production of the effector cytokines IL2 and IFNG after TCR engagement and for optimal induction of antibody responses to antigens. In epithelial cells stimulated with lysophosphatidic acid (LPA), is activated through a PKC-dependent pathway and mediates LPA-stimulated interleukin-8 (IL8) secretion via a NF-kappa-B-dependent pathway. During TCR-induced T-cell activation, interacts with and is activated by the tyrosine kinase LCK, which results in the activation of the NFAT transcription factors. In the trans-Golgi network (TGN), regulates the fission of transport vesicles that are on their way to the plasma membrane and in polarized cells is involved in the transport of proteins from the TGN to the basolateral membrane. Plays an important role in endothelial cell proliferation and migration prior to angiogenesis, partly through modulation of the expression of KDR/VEGFR2 and FGFR1, two key growth factor receptors involved in angiogenesis. In secretory pathway, is required for the release of chromogranin-A (CHGA)-containing secretory granules from the TGN. Downstream of PRKCA, plays important roles in angiotensin-2-induced monocyte adhesion to endothelial cells.
  • 亞細(xì)胞定位:
    Cytoplasm. Cell membrane. Golgi apparatus, trans-Golgi network.
  • 蛋白家族:
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 人妻少妇-嫩草影院| 国产乱人伦偷精品视频aaa| 在线精品国精品国产尤物| 久久狼人大香伊蕉国产| 久久婷婷是五月综合色| 亚洲一区二区三区播放| 亚洲中文字幕无码中文字在线| 小12萝8禁在线喷水观看| 无码国产一区二区三区四区| 欧美大屁股流白浆xxxx| 欧美午夜精品久久久久久浪潮| 2020每日更新国产精品视频| 欧美变态另类牲交| 无码人妻丰满熟妇a片护士| 草草影院发布页| 天堂国产一区二区三区| 国产精品嫩草影院久久| 97热久久免费频精品99| 亚洲午夜精品久久久久久浪潮| 国产精品国产三级国产av主播 | 精品国产成人一区二区三区| 日本高清中文字幕免费一区二区| 久久97超碰色中文字幕蜜芽| 无码国内精品人妻少妇蜜桃视频| 日本高清www午色夜com| 99久久精品国产成人综合| 无码专区丰满人妻斩六十路| 国产精品成人一区二区三区| 怡红院a∨人人爰人人爽| 国产香蕉国产精品偷在线| 天天天天噜在线视频| 久久精品无码av| 中国女人内谢69xxxxxa片| 久久精品免视看国产成人明星 | 欧美日韩一区二区三区自拍| 成人a大片在线观看| 在线观看国产精品普通话对白精品| 少妇荡乳情欲办公室456视频 | 亚洲香蕉成人av网站在线观看| 欧美人妻一区二区三区| 精品久久久久久国产|