在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Selenoprotein P (Sepp1)

  • 中文名稱:
    大鼠Selenop重組蛋白
  • 貨號:
    CSB-YP021018RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Selenop重組蛋白
  • 貨號:
    CSB-EP021018RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Selenop重組蛋白
  • 貨號:
    CSB-EP021018RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Selenop重組蛋白
  • 貨號:
    CSB-BP021018RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Selenop重組蛋白
  • 貨號:
    CSB-MP021018RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Selenop
  • Uniprot No.:
  • 別名:
    Selenop; Selp; Sepp1; Selenoprotein P; SeP) [Cleaved into: Selenoprotein Se-P10; Selenoprotein Se-P6; Selenoprotein Se-P2; Selenoprotein Se-P1]
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    20-385
  • 氨基酸序列
    E SQGQSPACKQ APPWNIGDQN PMLNSEGTVT VVALLQASUY LCLLQASRLE DLRIKLENQG YFNISYIVVN HQGSPSQLKH AHLKKQVSDH IAVYRQDEHQ TDVWTLLNGN KDDFLIYDRC GRLVYHLGLP YSFLTFPYVE EAIKIAYCEK RCGNCSFTSL EDEAFCKNVS SATASKTTEP SEEHNHHKHH DKHGHEHLGS SKPSENQQPG ALDVETSLPP SGLHHHHHHH KHKGQHRQGH LESUDMGASE GLQLSLAQRK LURRGCINQL LCKLSEESGA ATSSCCCHCR HLIFEKSGSA ITUQCAENLP SLCSUQGLFA EEKVIESCQC RSPPAAUHSQ HVSPTEASPN USUNNKTKKU KUNLN
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
  • 基因功能參考文獻:
    1. A chromatin immunoprecipitation (ChIP) assay revealed that EPA decreases binding of SREBP-1c to the SELENOP promoter. Knockdown of Srebf1 resulted in a significant down-regulation of Selenop expression. PMID: 28465347
    2. Data indicate that Selenoprotein P SEPP1 processivity is intrinsic, but efficiency is governed by selenium levels. PMID: 25063811
    3. metformin decreases binding of FoxO3a, a direct target of AMPK, to the SEPP1 promoter. PMID: 24257750
    4. Sepp1 secreted from epithelial cells may support the intestinal immune system by providing immune cells (including plasma cells) with selenium PMID: 24157689
    5. apoER2-mediated uptake of long isoform Sepp1 is responsible for selenium distribution to tissues throughout the body. PMID: 22761431
    6. investigation of Sepp1 expression in adipocytes during adipogenesis and oxidative stress in models of obesity and insulin resistance PMID: 20959537
    7. tear SeP is a key molecule to protect the ocular surface cells against environmental oxidative stress PMID: 20360971
    8. mass spectrometric characterization of full-length protein and three isoforms shortened at the C terminus PMID: 11821412
    9. selenenylsulfide linkages Sec304-Cys314 and Cys306-Sec316 were present; selenoprotein P contains these two selenenylsulfide bonds PMID: 15712351
    10. Sertoli cell ApoER2 is a Sepp1 receptor and a component of the selenium delivery pathway to spermatogenic cells PMID: 17314095
    11. In conclusion, the selenoprotein P promoter is a target of the Akt/FoxO signal transduction cascade and SeP expression is regulated at the level of transcription by the forkhead box protein FoxO1a in human and rat hepatoma cells. PMID: 17986386

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Selenoprotein P family
  • 組織特異性:
    Widely expressed, mainly by the liver. Secreted in plasma.
  • 數據庫鏈接:

    KEGG: rno:29360

    UniGene: Rn.1451



主站蜘蛛池模板: 亚洲熟妇av一区二区三区漫画| 韩国国内大量揄拍精品视频 | 久久久久久久久久久久| 国产99久久久久久免费看| 久久精品久久电影免费理论片 | 国产成人综合久久免费导航| 欧美影院成年免费版| 日韩一区二区三区精品| 国产福利姬喷水福利在线观看| 精品多人p群无码| 色88久久久久高潮综合影院| 欧洲成人一区二区三区| 18禁无遮挡无码网站免费| 国产婷婷亚洲999精品小说| 欧美成aⅴ人高清ww| 人妻无码中文久久久久专区| 成人毛片无码一区二区三区| 高潮喷吹一区二区在线观看| 国产sp调教打屁股视频网站| 长腿校花无力呻吟娇喘的视频 | 日韩视频无码免费一区=区三区 | 极品少妇xxxx精品少妇偷拍| 人人爽人人澡人人高潮| 双腿高潮抽搐喷白浆视频| 久久性色av亚洲电影| 亚洲精品国产一区二区精华液| 波多野结衣av在线无码中文18| 日韩国产精品人妻无码久久久| 国产精品福利视频导航| 亚洲中文字幕无码爆乳app| 国产熟妇午夜精品aaa| 亚洲欧洲综合有码无码| av无码精品一区二区三区四区| 99久久99久久精品国产片| 肉感饱满中年熟妇日本| 国产精品卡一卡2卡三卡网站| 一区二区视频| 国产乱子伦三级在线播放| av永久天堂一区| 免费又黄又硬又爽大片| 少妇被粗大的猛进69视频|