在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Selenoprotein P (Sepp1)

  • 中文名稱:
    大鼠Selenop重組蛋白
  • 貨號:
    CSB-YP021018RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Selenop重組蛋白
  • 貨號:
    CSB-EP021018RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Selenop重組蛋白
  • 貨號:
    CSB-EP021018RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Selenop重組蛋白
  • 貨號:
    CSB-BP021018RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Selenop重組蛋白
  • 貨號:
    CSB-MP021018RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Selenop
  • Uniprot No.:
  • 別名:
    Selenop; Selp; Sepp1; Selenoprotein P; SeP) [Cleaved into: Selenoprotein Se-P10; Selenoprotein Se-P6; Selenoprotein Se-P2; Selenoprotein Se-P1]
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    20-385
  • 氨基酸序列
    E SQGQSPACKQ APPWNIGDQN PMLNSEGTVT VVALLQASUY LCLLQASRLE DLRIKLENQG YFNISYIVVN HQGSPSQLKH AHLKKQVSDH IAVYRQDEHQ TDVWTLLNGN KDDFLIYDRC GRLVYHLGLP YSFLTFPYVE EAIKIAYCEK RCGNCSFTSL EDEAFCKNVS SATASKTTEP SEEHNHHKHH DKHGHEHLGS SKPSENQQPG ALDVETSLPP SGLHHHHHHH KHKGQHRQGH LESUDMGASE GLQLSLAQRK LURRGCINQL LCKLSEESGA ATSSCCCHCR HLIFEKSGSA ITUQCAENLP SLCSUQGLFA EEKVIESCQC RSPPAAUHSQ HVSPTEASPN USUNNKTKKU KUNLN
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
  • 基因功能參考文獻:
    1. A chromatin immunoprecipitation (ChIP) assay revealed that EPA decreases binding of SREBP-1c to the SELENOP promoter. Knockdown of Srebf1 resulted in a significant down-regulation of Selenop expression. PMID: 28465347
    2. Data indicate that Selenoprotein P SEPP1 processivity is intrinsic, but efficiency is governed by selenium levels. PMID: 25063811
    3. metformin decreases binding of FoxO3a, a direct target of AMPK, to the SEPP1 promoter. PMID: 24257750
    4. Sepp1 secreted from epithelial cells may support the intestinal immune system by providing immune cells (including plasma cells) with selenium PMID: 24157689
    5. apoER2-mediated uptake of long isoform Sepp1 is responsible for selenium distribution to tissues throughout the body. PMID: 22761431
    6. investigation of Sepp1 expression in adipocytes during adipogenesis and oxidative stress in models of obesity and insulin resistance PMID: 20959537
    7. tear SeP is a key molecule to protect the ocular surface cells against environmental oxidative stress PMID: 20360971
    8. mass spectrometric characterization of full-length protein and three isoforms shortened at the C terminus PMID: 11821412
    9. selenenylsulfide linkages Sec304-Cys314 and Cys306-Sec316 were present; selenoprotein P contains these two selenenylsulfide bonds PMID: 15712351
    10. Sertoli cell ApoER2 is a Sepp1 receptor and a component of the selenium delivery pathway to spermatogenic cells PMID: 17314095
    11. In conclusion, the selenoprotein P promoter is a target of the Akt/FoxO signal transduction cascade and SeP expression is regulated at the level of transcription by the forkhead box protein FoxO1a in human and rat hepatoma cells. PMID: 17986386

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Selenoprotein P family
  • 組織特異性:
    Widely expressed, mainly by the liver. Secreted in plasma.
  • 數據庫鏈接:

    KEGG: rno:29360

    UniGene: Rn.1451



主站蜘蛛池模板: 午夜福利国产成人a∨在线观看| 国产成人精品亚洲777人妖| 国产又色又爽又黄的免费| 精品久久久久久无码人妻热| 久激情内射婷内射蜜桃| 亚洲人成网站在线播放2019| 久久精品国产9久久综合| 狠狠色老熟妇老熟女| av无码天一区二区一三区| 夜夜躁很很躁日日躁麻豆| 亚洲一区二区三区写真| 99久久久无码国产精品古装| 老司机久久99久久精品播放免费| 中文国产成人精品久久久 | 久久久久国色av∨免费看| 欧美亚洲精品一区二区| 影音先锋女人aa鲁色资源| 日韩精品一区二区三区在线观看l| 另类国产精品一区二区| 精品免费国偷自产在线视频| 999久久久免费精品国产| 中文字幕人妻无码视频| 中文精品无码中文字幕无码专区 | 污污污污污污www网站免费| 性无码免费一区二区三区在线| 日韩新无码精品毛片| 亚洲精品久久一区二区无卡| 国产午夜成人免费看片app| 美女脱了内裤张开腿让男人桶网站| 女人和拘做爰正片视频| 交换交换乱杂烩系列yy| 国产精品久久久久久久伊一| 国产人成视频在线观看| 欧美 日韩 人妻 高清 中文| 内射人妻无套中出无码| 国产做a爰片久久毛片a片白丝| 婷婷成人小说综合专区| 精品乱人伦一区二区三区 | 上海少妇高潮狂叫喷水了| 下面一进一出好爽视频| 亚洲欧美国产毛片在线|