在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Platelet-activating factor acetylhydrolase IB subunit alpha (Pafah1b1)

  • 中文名稱:
    大鼠Pafah1b1重組蛋白
  • 貨號:
    CSB-YP017383RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Pafah1b1重組蛋白
  • 貨號:
    CSB-EP017383RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Pafah1b1重組蛋白
  • 貨號:
    CSB-EP017383RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Pafah1b1重組蛋白
  • 貨號:
    CSB-BP017383RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Pafah1b1重組蛋白
  • 貨號:
    CSB-MP017383RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Pafah1b1
  • Uniprot No.:
  • 別名:
    Pafah1b1; Lis-1; Lis1; Pafaha; Platelet-activating factor acetylhydrolase IB subunit alpha; Lissencephaly-1 protein; LIS-1; PAF acetylhydrolase 45 kDa subunit; PAF-AH 45 kDa subunit; PAF-AH alpha; PAFAH alpha
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-410
  • 氨基酸序列
    MVLSQRQRDE LNRAIADYLR SNGYEEAYSV FKKEAELDMN EELDKKYAGL LEKKWTSVIR LQKKVMELES KLNEAKEEFT SGGPLGQKRD PKEWIPRPPE KYALSGHRSP VTRVIFHPVF SVMVSASEDA TIKVWDYETG DFERTLKGHT DSVQDISFDH SGKLLASCSA DMTIKLWDFQ GFECIRTMHG HDHNVSSVAI MPNGDHIVSA SRDKTIKMWE VQTGYCVKTF TGHREWVRMV RPNQDGTLIA SCSNDQTVRV WVVATKECKA ELREHEHVVE CISWAPESSY SSISEATGSE TKKSGKPGPF LLSGSRDKTI KMWDVSTGMC LMTLVGHDNW VRGVLFHSGG KFILSCADDK TLRVWDYKNK RCMKTLNAHE HFVTSLDFHK TAPYVVTGSV DQTVKVWECR
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulatory subunit (beta subunit) of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)), an enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and participates in PAF inactivation. Regulates the PAF-AH (I) activity in a catalytic dimer composition-dependent manner. Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing. Required for dynein recruitment to microtubule plus ends and BICD2-bound cargos. May modulate the Reelin pathway through interaction of the PAF-AH (I) catalytic dimer with VLDLR.
  • 基因功能參考文獻:
    1. Data suggest that binding of Lis1 to DDB complex does not strongly disrupt processive motility along microtubules; motile DDB complex binds up to two Lis1 dimers; mutational analysis suggested that Lis1 binds directly to the dynein motor domains during DDB complex movement. (Lis1 = lissencephaly 1 protein; DDB complex = dynein-dynactin-BicD2 complex; BicD2 = bicaudal D homolog 2 protein) PMID: 28576829
    2. LIS1 interacts with KIF5b and regulates mitochondrial axonal transport in both anterograde and retrograde directions. PMID: 23551859
    3. Mutually exclusive cytoplasmic dynein regulation by NudE-Lis1 and dynactin. PMID: 21911489
  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus membrane.
  • 蛋白家族:
    WD repeat LIS1/nudF family
  • 組織特異性:
    Expressed in most tissues, with highest expression in brain. Expressed in fetal and adult brain. In neural cells, expressed in granule cells, astroglial cells, and oligodendrocytes.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲国产av无码一区二区三区| 玩弄japan白嫩少妇hd| 国产三区在线成人av| 天干天干夜啦天干天干国产 | 久久精品国产99国产精2020丨 | 天天爱天天做天天做天天吃中文| 99热国产这里只有精品6| 亚洲国产精品无码久久秋霞| 亚洲中文字幕无码久久| 国产高清成人免费视频在线观看| 国产影片av级毛片特别刺激| 国产精品国产三级在线...| 国语自产精品视频在线看| 欧美成人精品高清视频在线观看 | 国产高潮又爽又刺激的视频| 四虎成人国产精品永久在线 | 免费无人区男男码卡二卡| 欲色欲色天天天www| 全免费又大粗又黄又爽少妇片| 日本免费人成视频播放| 日韩精品一区二区三区影院| 国产成+人+综合+亚洲欧美| 国产乱xxⅹxx国语对白| 色偷偷av男人的天堂| 国产视频亚洲精品视频| 少妇高潮喷水正在播放| 亚洲精品乱码久久久久久蜜桃图片| 一本久道久久综合狠狠躁av| 乱码精品一区二区三区| 亚洲人成色777777老人头| 国产真实夫妇交换视频| 青乐娱精品视频一国产分类| 亚洲综合色无码| 欧美日韩一区二区三区视频播放 | 亚洲中文有码字幕日本| 亚洲一区av无码专区在线观看| 亚洲一区av无码少妇电影| 12裸体自慰免费观看网站| 大胸少妇午夜三级| 国语国产精精品国产国语清晰对话| 欧洲无码精品a码无人区|