在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat NACHT, LRR and PYD domains-containing protein 6 (Nlrp6), partial

Recombinant Rat NACHT, LRR and PYD domains-containing protein 6 (Nlrp6), partial

  • 中文名稱：
    大鼠Nlrp6重組蛋白
  • 貨號(hào)：
    CSB-YP714101RA
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Nlrp6重組蛋白
  • 貨號(hào)：
    CSB-EP714101RA
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Nlrp6重組蛋白
  • 貨號(hào)：
    CSB-EP714101RA-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Nlrp6重組蛋白
  • 貨號(hào)：
    CSB-BP714101RA
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Nlrp6重組蛋白
  • 貨號(hào)：
    CSB-MP714101RA
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Nlrp6; Nalp6; Navr; Pypaf5; NACHT; LRR and PYD domains-containing protein 6; Angiotensin II/vasopressin receptor; Non-angiotensin-vasopressin receptor; Non-AVR; PYRIN-containing APAF1-like protein 5-like
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    As the sensor component of the NLRP6 inflammasome, plays a crucial role in innate immunity and inflammation. In response to yet unidentified signals, initiates the formation of the inflammasome polymeric complex, made of NLRP6, PYCARD and CASP1. Recruitment of proCASP1 to the inflammasome promotes its activation and CASP1-catalyzed IL1B and IL18 maturation and secretion in the extracellular milieu. The precise NLRP6 activation stimulus has not been identified yet. Essential for gut mucosal self-renewal and proliferation. Maintains intestinal homeostasis and a healthy intestinal microbiota. This function is, at least partially, mediated by IL18, and not IL1B, produced by nonhematopoietic cells. Influences intestinal barrier function and microbial homeostasis through the regulation of goblet cell mucus secretion. Acts by promoting autophagy in goblet cells, an essential step for mucus granule exocytosis. Its role in goblet cell physiology is inflammasome-dependent, but IL1B- and IL18-independent. During systemic bacterial infections, may negatively regulate inflammatory signaling and inhibit the influx of monocytes and neutrophils to the circulation and to the peritoneum. May promote peripheral nerve recovery following injury via an inflammasome-independent mechanism.
  • 基因功能參考文獻(xiàn)：
    1. AVR is distinct from Nalp6/PYPAF5 based on different mRNA and protein sizes, subcellular localization, and tissue-specific expression patterns. PMID: 18413781
    2. The dual AngII/AVP receptor gene N119S/C163R variant exhibits sodium-induced dysfunction and cosegregates with salt-sensitive hypertension in the Dahl salt-sensitive hypertensive rat model. PMID: 11984003
  • 相關(guān)疾病：
    Defects in Nlrp6 may be a cause of salt-sensitive hypertension.
  • 亞細(xì)胞定位：
    [Isoform 1]: Cytoplasm. Inflammasome. Cell membrane. Nucleus membrane.; [Isoform 2]: Cytoplasm. Cell membrane. Note=Predominantly expressed at the cell membrane.
  • 蛋白家族：
    NLRP family
  • 組織特異性：
    Detected in several tissues. Expressed in renal epithelial cells in medullary thick ascending limb of Henle, as well as in salivary gland apical epithelium (at protein level). Isoform 1 is widely expressed. Isoform 2 is primarily expressed in kidney (at p
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 2018年秋霞无码片| 国产精品久久久久7777| 国产精品无码mv在线观看| 中文天堂最新版在线www| 激情综合五月丁香亚洲| 精品欧美成人高清在线观看 | 国产国拍亚洲精品av在线| h肉动漫无码无修6080动漫网| 国产区精品系列在线观看| 午夜免费啪视频在线观看区| 国产全肉乱妇杂乱视频| 色噜噜狠狠一区二区三区| 狠狠躁夜夜躁人人爽天天| 曰韩a∨无码一区二区三区| 色老头在线一区二区三区| 50路60路老熟妇啪啪| 久久婷婷色香五月综合缴缴情| 亚洲国产成人久久一区久久| 国产亚洲精品成人aa片| 麻豆一区二区三区精品视频| 欧美老妇bbbwwbbbww| 少妇乳大丰满在线播放| 亚洲日韩欧美一区二区三区| 天堂在线最新版资源www中文| 国产私拍大尺度在线视频| 欧美午夜片欧美片在线观看| 综合色就爱涩涩涩综合婷婷| av午夜福利一片免费看久久| 亚洲熟熟妇xxxx| 久久香蕉国产线看观看手机| 免费网站内射红桃视频| 成熟女人牲交片免费观看视频| 少妇挑战三个黑人惨叫4p国语| 一本一道中文字幕无码东京热| 69国产成人精品午夜福中文| 99国内精品久久久久久久| 日韩插啊免费视频在线观看| 人人妻人人澡人人爽欧美精品| 一二三四在线视频社区3| av大片在线无码永久免费| 国内精品久久久久影院网站|