在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Lymphocyte activation gene 3 protein (Lag3), partial

Recombinant Rat Lymphocyte activation gene 3 protein (Lag3), partial

  • 中文名稱：
    大鼠Lag3重組蛋白
  • 貨號：
    CSB-YP704714RA
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Lag3重組蛋白
  • 貨號：
    CSB-EP704714RA
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Lag3重組蛋白
  • 貨號：
    CSB-EP704714RA-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Lag3重組蛋白
  • 貨號：
    CSB-BP704714RA
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Lag3重組蛋白
  • 貨號：
    CSB-MP704714RA
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Lag3; Lymphocyte activation gene 3 protein; LAG-3; CD antigen CD223) [Cleaved into: Secreted lymphocyte activation gene 3 protein; sLAG-3)]
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells. Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell inhibitory function. Following TCR engagement, LAG3 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation. May inhibit antigen-specific T-cell activation in synergy with PDCD1/PD-1, possibly by acting as a coreceptor for PDCD1/PD-1. Negatively regulates the proliferation, activation, effector function and homeostasis of both CD8(+) and CD4(+) T-cells. Also mediates immune tolerance: constitutively expressed on a subset of regulatory T-cells (Tregs) and contributes to their suppressive function. Also acts as a negative regulator of plasmacytoid dendritic cell (pDCs) activation. Binds MHC class II (MHC-II); the precise role of MHC-II-binding is however unclear.; May function as a ligand for MHC class II (MHC-II) on antigen-presenting cells (APC), promoting APC activation/maturation and driving Th1 immune response.
  • 基因功能參考文獻：
    1. cloning and mRNA expression; Lag3 mRNA was mainly expressed in lymphoid tissues PMID: 15009174
    2. LAG-3 binds to a minority of histocompatibility class II-positive cells in peripheral blood mononuclear leukocytes, including all myeloid dendritic cells, and a small fraction of monocytes. PMID: 17785860
    3. Targeting LAG-3-positive cells with cytotoxic antibodies is immunosuppressive in transplantation by depleting effectors T cells PMID: 18091527
  • 亞細胞定位：
    [Lymphocyte activation gene 3 protein]: Cell membrane; Single-pass type I membrane protein.; [Secreted lymphocyte activation gene 3 protein]: Secreted.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲成a∧人片在线播放无码| 色噜噜狠狠色综合日日| 黑人巨茎大战欧美白妇| 亚洲精品尤物av在线观看不卡 | 性色av极品无码专区亚洲| 一区二区三区四区在线 | 中国 | 国产综合精品一区二区三区| 亚洲色大成网站www永久一区| 玩弄丰满熟妇xxxxx性60| 婷婷丁香五月缴情视频| 国产精品午夜无码av天美传媒| 久久天天躁狠狠躁夜夜av | 亚洲国产v高清在线观看| 国产午夜人做人免费视频网站| av永久天堂一区二区三区| 精品免费久久久久久久| 乱中年女人伦av一区二区| 午夜无码性爽快影院6080| 国内乱码一线二线三线| 成人无码精品1区2区3区免费看| 麻豆精品国产精华精华液好用吗| 国产精品亚洲精品一区二区| 久久精品国产清高在天天线| 国产成人a人亚洲精v品无码| 久久妇女高潮喷水多| 亚洲色婷婷六月亚洲婷婷6月| 草草影院精品一区二区三区| 色婷婷五月综合色啪网| 久久精品国产亚洲7777| 久久精品无码一区二区三区 | 热の综合热の国产热の潮在线| 国产在线精品一区二区三区 | 无码无套少妇18p在线直播| 日韩精品 中文字幕 视频在线| 国产精品理论片| 亚洲国产一区二区波多野结衣| 亚洲中文欧美在线视频| 国产成人欧美一区二区三区| 免费观看羞羞视频网站| 国产亚洲精品欧洲在线视频| 天堂网www天堂资源网|