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  4. Recombinant Rat Leukotriene A-4 hydrolase (Lta4h)

Recombinant Rat Leukotriene A-4 hydrolase (Lta4h)

  • 中文名稱：
    大鼠Lta4h重組蛋白
  • 貨號：
    CSB-YP013219RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Lta4h重組蛋白
  • 貨號：
    CSB-EP013219RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Lta4h重組蛋白
  • 貨號：
    CSB-EP013219RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Lta4h重組蛋白
  • 貨號：
    CSB-BP013219RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Lta4h重組蛋白
  • 貨號：
    CSB-MP013219RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Lta4h; Leukotriene A-4 hydrolase; LTA-4 hydrolase; EC 3.3.2.6; Leukotriene A(4) hydrolase
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-610
  • 氨基酸序列
    PEVEDTCSL ASPASVCRTQ HLHLRCSVDF ARRALTGTAA LTVQSQEDNL RTLTLDTKDL TIEKVVINGQ EVKYTLGESQ GYKGSPMEIS LPIALSKNQE VVIEISFETS PKSSALQWLT PEQTSGKQHP YLFSQWEAIH CRAILPCQDT SVKLTYTAEV SVPKELVALM SAIRDGEAPD PEDPSRKIYR FNQRVPIPCY LIALVVGALE SRQIGPRTLV WSEKEQVEKS AYEFSETESM LKIAEDLGGP YVWGQYDLLV LPPSFPYGGM ENPCLTFVTP TLLAGDKSLS NVIAHEISHS WTGNLVTNKT WDHFWLNEGH TVYLERHICG RLFGEKFRHF HALGGWGELQ NTIKTFGESH PFTKLVVDLK DVDPDVAYSS IPYEKGFALL FYLEQLLGGP EVFLGFLKAY VEKFSYQSVT TDDWKSFLYA HFKDKVDLLN QVDWNAWLYA PGLPPVKPNY DVTLTNACIA LSQRWVTAKE EDLNSFSIED LKDLSSHQLN EFLAQVLQRA PLPLGHIKRM QEVYNFNAIN NSEIRFRWLR LCIQSKWEEA IPLALKMATE QGRMKFTRPL FKDLAAFDKS HDQAVRTYQE HKACMHPVTA MLVGKDLKVD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Bifunctional zinc metalloenzyme that comprises both epoxide hydrolase (EH) and aminopeptidase activities. Acts as an epoxide hydrolase to catalyze the conversion of LTA4 to the proinflammatory mediator leukotriene B4 (LTB4). Has also aminopeptidase activity, with high affinity for N-terminal arginines of various synthetic tripeptides. In addition to its proinflammatory EH activity, may also counteract inflammation by its aminopeptidase activity, which inactivates by cleavage another neutrophil attractant, the tripeptide Pro-Gly-Pro (PGP), a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP9) and prolylendopeptidase (PREPL). Involved also in the biosynthesis of resolvin E1 and 18S-resolvin E1 from eicosapentaenoic acid, two lipid mediators that show potent anti-inflammatory and pro-resolving actions.
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Peptidase M1 family
  • 數據庫鏈接：


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