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Recombinant Rat Laminin subunit beta-2 (Lamb2), partial

  • 中文名稱:
    大鼠Lamb2重組蛋白
  • 貨號:
    CSB-YP012731RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Lamb2重組蛋白
  • 貨號:
    CSB-EP012731RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Lamb2重組蛋白
  • 貨號:
    CSB-EP012731RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Lamb2重組蛋白
  • 貨號:
    CSB-BP012731RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Lamb2重組蛋白
  • 貨號:
    CSB-MP012731RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Lamb2; Laminin subunit beta-2; Laminin chain B3; Laminin-11 subunit beta; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-3 subunit beta; Laminin-4 subunit beta; Laminin-7 subunit beta; Laminin-9 subunit beta; S-laminin subunit beta; S-LAM beta
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
  • 基因功能參考文獻:
    1. Crystallographic analysis of the LAMB2 short arm reveals how the LF domain is inserted into a regular array of LE domains. PMID: 27425256
    2. Together, these studies provide evidence for regulation of Lamb2 translation by IMP2, an RNA binding protein that targets Lamb2 mRNA to the actin cytoskeleton. PMID: 22513850
    3. R246Q mutation causes nephrotic syndrome by impairing secretion of laminin-521 from podocytes into the glomerular basement membrane (GBM). PMID: 21511833
  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix, basement membrane.
  • 組織特異性:
    Found in the basement membranes (major component). S-laminin is concentrated in the synaptic cleft of the neuromuscular junction.
  • 數據庫鏈接:

    KEGG: rno:25473

    STRING: 10116.ENSRNOP00000065052

    UniGene: Rn.774



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