Recombinant Rat Janus kinase and microtubule-interacting protein 1 (Jakmip1)

中文名稱：

大鼠Jakmip1重組蛋白
貨號：

CSB-YP663560RA
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Jakmip1重組蛋白
貨號：

CSB-EP663560RA
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Jakmip1重組蛋白
貨號：

CSB-EP663560RA-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Jakmip1重組蛋白
貨號：

CSB-BP663560RA
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Jakmip1重組蛋白
貨號：

CSB-MP663560RA
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Jakmip1
Uniprot No.：

Q3SWS9
別名：

Jakmip1; Marlin1; Janus kinase and microtubule-interacting protein 1; Multiple alpha helices and RNA-linker protein 1; Marlin-1
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-626
氨基酸序列

MSKKGRSKGE KPETETDSVQ MANEELRAKL TNIQIEFQQE KSKVGKLRER LQEAKLEREQ EQRRHTAYIS ELKAKLHEEK TKELQALREA LIRQHEQEAA RTAKIKEGEL QRLQATLNVL RDGAADKVKT ALLADAREEA RRTFDGERQR LQQEILELKA ARKQAEEALS NCMQADKAKA ADLRAAYQAH QDEVHRIKRE CERDIRRLMD EIKGKERVIL ALEKELGVQA GQTQRLLLQK EALDEQLVQV KEAERHHSSP KRELPPGIGD MAELMGGQDQ HMDERDVRRF QLKIAELNSV IRKLEDRNTL LADERNELLK RSRETEVQLK PLVEKNKRMN KKNEDLLHSI QRMEEKLKSL TRENVEMKEK LSAQASLKRH TSLNDLSLTR DEQEIEFLRL QVLEQQHVID DLSLERERLL RSKRHRGKSL KPPKKHVVET FFGFDEESVD SETLSETSYN TDRTDRTPAT PEEDLDETTT REEADLRFCQ LTREYQALQR AYALLQEQVG GTLDAEREAR TREQLQADLL RCQAKIEDLE KLLVEKGQDA AWVEEKQVLM RTNQDLLEKI YRLEMEENQL KSEMQDAKDQ NELLEFRVLE LEVRDSICCK LSNGADILFE PKLKFV
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
基因功能參考文獻(xiàn)：
1. Marlin-1 is enriched in restricted areas of the brain including olfactory bulb, cerebral cortex, hippocampus and cerebellum; it is abundant in dendrites and axons of hippocampal neurons, associated with microtubules at the ultrastructural level. PMID: 19386132
2. Marlin-1 functions to regulate the cellular levels of GABA(B) R2 subunits, which may have significant effects on the production of functional GABA(B) receptor heterodimers. PMID: 14718537
3. RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal neurons during the formation of the cortex. PMID: 22828129
亞細(xì)胞定位：

Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.
蛋白家族：

JAKMIP family
組織特異性：

Specifically expressed in brain and testis by spermatogonia, spermatocytes, spermatozoa and Sertoli cells (at protein level).
數(shù)據(jù)庫鏈接：

KEGG: rno:305434

STRING: 10116.ENSRNOP00000006771

UniGene: Rn.18970