在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Interleukin-17A (Il17a)

  • 中文名稱:
    大鼠Il17a重組蛋白
  • 貨號:
    CSB-YP717213RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Il17a重組蛋白
  • 貨號:
    CSB-EP717213RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Il17a重組蛋白
  • 貨號:
    CSB-BP717213RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Il17a重組蛋白
  • 貨號:
    CSB-MP717213RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Il17a; Ctla8; Il17Interleukin-17A; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    18-150
  • 氨基酸序列
    AVL IPQSSVCPNA EANNFLQNVK VNLKVINSLS SKASSRRPSD YLNRSTSPWT LSRNEDPDRY PSVIWEAQCR HQRCVNAEGK LDHHMNSVLI QQEILVLKRE PEKCPFTFRV EKMLVGVGCT CVSSIVRHAS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter. This leads to downstream TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation. Plays an important role in connecting T cell-mediated adaptive immunity and acute inflammatory response to destroy extracellular bacteria and fungi. As a signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites. In airway epithelium, mediates neutrophil chemotaxis via induction of CXCL1 and CXCL5 chemokines. In secondary lymphoid organs, contributes to germinal center formation by regulating the chemotactic response of B cells to CXCL12 and CXCL13, enhancing retention of B cells within the germinal centers, B cell somatic hypermutation rate and selection toward plasma cells. Effector cytokine of a subset of gamma-delta T cells that functions as part of an inflammatory circuit downstream IL1B, TLR2 and IL23A-IL12B to promote neutrophil recruitment for efficient bacterial clearance. Effector cytokine of innate immune cells including invariant natural killer cell (iNKT) and group 3 innate lymphoid cells that mediate initial neutrophilic inflammation. Involved in the maintenance of the integrity of epithelial barriers during homeostasis and pathogen infection. Upon acute injury, has a direct role in epithelial barrier formation by regulating OCLN localization and tight junction biogenesis. As part of the mucosal immune response induced by commensal bacteria, enhances host's ability to resist pathogenic bacterial and fungal infections by promoting neutrophil recruitment and antimicrobial peptides release. In synergy with IL17F, mediates the production of antimicrobial beta-defensins DEFB1, DEFB103A, and DEFB104A by mucosal epithelial cells, limiting the entry of microbes through the epithelial barriers. Involved in antiviral host defense through various mechanisms.
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    IL-17 family
  • 數據庫鏈接:


主站蜘蛛池模板: 无码任你躁久久久久久| 狂野欧美激情性xxxx在线观看| 国产午夜无码片在线观看| 中文字幕日韩人妻在线视频| 天堂资源在线www中文| 日本狂喷奶水在线播放212| 国产成人av乱码免费观看| 亚洲精品乱码久久久久久中文字幕| 国产精品99久久精品爆乳| 久久伊人精品波多野结衣| 西西艺术人像摄影| 国产精品久久| 国产97色在线 | 日韩| 久久精品日日躁夜夜躁欧美| 日韩免费无砖专区2020狼| 久久www色情成人免费观看| 小荡货好紧好爽奶头大视频| 亚洲日韩av无码一区二区三区 | 波多野结衣一区二区三区av免费| 国产精品偷窥熟女精品视频| 日日摸日日添日日碰9学生露脸| 国产成人无码va在线观看| 日本乱理伦片在线观看中文| av永久天堂一区二区三区| 米奇影视第四色| 国产成人av片无码免费| 国产又黄又爽胸又大免费视频| 亂倫近親相姦中文字幕| av无码中文一区二区三区四区| 无码人妻专区免费视频| 97熟女毛毛多熟妇人妻aⅴ| 久久久99久久久国产自输拍| 在线播放五十路熟妇| 久久久国产成人一区二区| 亚洲精品久久66国产高清| 激情爆乳一区二区三区| 风流老熟女一区二区三区| 日本在线a一区视频| 国产精品亚洲а∨无码播放麻豆| 中文字幕乱码中文乱码777| 在线精品视频一区二区|