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  4. Recombinant Rat G2/mitotic-specific cyclin-B1 (Ccnb1)

Recombinant Rat G2/mitotic-specific cyclin-B1 (Ccnb1)

  • 中文名稱：
    Recombinant Rat G2/mitotic-specific cyclin-B1(Ccnb1)
  • 貨號(hào)：
    CSB-YP004806RA
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat G2/mitotic-specific cyclin-B1(Ccnb1)
  • 貨號(hào)：
    CSB-EP004806RA
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat G2/mitotic-specific cyclin-B1(Ccnb1)
  • 貨號(hào)：
    CSB-EP004806RA-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat G2/mitotic-specific cyclin-B1(Ccnb1)
  • 貨號(hào)：
    CSB-BP004806RA
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat G2/mitotic-specific cyclin-B1(Ccnb1)
  • 貨號(hào)：
    CSB-MP004806RA
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Ccnb1G2/mitotic-specific cyclin-B1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Full length protein
  • 表達(dá)區(qū)域：
    1-423
  • 氨基酸序列
    MALRVTRNTK INTENKAKVS MAGAKRVPVA VAASKPLLRS RTALGDIGNK VSEQSRIPLK KETKKLGSGT VTVKALPKPV DKVPVCEPEV ELDEPEPEPV MEVKHSPEPI LVDTPSPSPM ETSGCAPAEE YLCQAFSDVI LAVSDVDADD GGDPNLCSEY VKDIYAYLRQ LEEEQSVRPK YLLGREVTGN MRAILIDWLI QVQMKFRLLQ ETMYMTVSII DRFMQDSCVP KKMLQLVGVT AMFIASKYEE MYPPEIGDFA FVTNNTYTKH QIRQMEMKIL RVLNFSLGRP LPLHFLRRAS KIGEVDVEQH TLAKYLMELS MLDYDMVHFA PSQIAAGAFC LALKILDNGE WTPTLQHYLS HTEESLLPVM QHLAKNIVMV NRGLTKHMTI KNKYATSKHA KISTLAQLNC TLVQNLSKAV TKA
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Essential for the control of the cell cycle at the G2/M (mitosis) transition.
  • 基因功能參考文獻(xiàn)：
    1. These results unveil a previously unrecognized role for mitochondrial cyclin B1 in the oxidative damage associated with neurological disorders. PMID: 26109654
    2. that MAD2B may play an important role in high glucose-mediated podocyte injury of diabetic nephropathy via modulation of Cdh1, cyclin B1, and Skp2 expression PMID: 25651564
    3. Expression of cyclin B1 mRNA and localization of cyclin B1 protein are dependent on the developmental stages of spermatogenic cells. PMID: 12399820
    4. Data show that cyclin A1 and cyclin B1 gene expression is controlled by E(2) at a concentration of 10(-9)uM only in stages IX-I of spermatogenesis. PMID: 22180637
    5. Cytoplasmic polyadenylation element binding protein 1 (CPEB1) is associated with cyclin B1 mRNA; this interaction is enriched at the centrosome. PMID: 21865454
    6. introduction of cyclin B1 dsRNA into rat oocytes selectively depleted the corresponding mRNA, further ablating its protein product PMID: 15291744
    7. Cdc2/cyclin B1 interacts with and modulates inositol 1,4,5-trisphosphate receptor (type 1) functions. PMID: 16237118
    8. analysis of expression of Cyclin D1, E, A and B1 in neurons of cerebral cortex and hippocampus PMID: 18278459
    9. the expressions of Swedish double mutation of amyloid precursor protein (Swe-APP)increased mRNA and protein levels of cyclin D1 and cyclin B1 PMID: 18438935
    10. Data show that aberrant expression of cyclin B1 takes place in the brain after chronic cerebral hypoperfusion in retired rat. PMID: 18775106
    11. Cdh1 is a novel Cdk5 substrate that mediates cyclin B1 neuronal accumulation in excitotoxicity PMID: 18818692

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  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 蛋白家族：
    Cyclin family, Cyclin AB subfamily
  • 數(shù)據(jù)庫鏈接：


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