在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Dynamin-2 (Dnm2), partial

Recombinant Rat Dynamin-2 (Dnm2), partial

  • 中文名稱：
    大鼠Dnm2重組蛋白
  • 貨號：
    CSB-YP007079RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Dnm2重組蛋白
  • 貨號：
    CSB-EP007079RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Dnm2重組蛋白
  • 貨號：
    CSB-EP007079RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Dnm2重組蛋白
  • 貨號：
    CSB-BP007079RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Dnm2重組蛋白
  • 貨號：
    CSB-MP007079RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Dnm2; Dyn2Dynamin-2; EC 3.6.5.5
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane.
  • 基因功能參考文獻：
    1. Study is the first to show the association of dynamin Charcot-Marie-Tooth disease mutations with aberrant actin dynamics and lamellipodia, which may contribute to defective endocytosis and myelination in Schwann cells in Charcot-Marie-Tooth disease. PMID: 27328317
    2. Reduction in dynamin-2 is implicated in ischaemic cardiac arrhythmias. PMID: 25092467
    3. dynamin2 orchestrates the global actin cytoskeleton PMID: 24710573
    4. Disruption of the DNM2-dependent retrograde trafficking of NHE1 contributes to cardiomyocyte apoptosis. PMID: 23837875
    5. dynamin isoforms select appropriate vesicle reuse pathways associated with specific neuronal firing patterns PMID: 23687302
    6. This study suggested that myelination is strictly dependent on Dnm2 and clathrin-mediated endocytosis function. PMID: 22451505
    7. ITSN-1s, via its SH3A domain has the unique ability to regulate dyn2 assembly-disassembly and function during endocytosis PMID: 21129155
    8. Dynamin 2 and cortactin co-localize in advancing growth cones of embryonic hippocampal neurons. PMID: 21210813
    9. Dynamin 2 is primarily tetrameric throughout the entire cell membrane. PMID: 21281565
    10. These findings support the view that endophilin-dynamin interactions play an important role in endocytosis. PMID: 21281588
    11. Formation of abnormally large and stable complexes of these dynamin mutants in vivo contributes to their role in centronuclear myopathies pathogenesis PMID: 20529869
    12. Role of the proline-rich domain of dynamin-2 and its interactions with Src homology 3 domains during endocytosis of the AT1 angiotensin receptor PMID: 11925437
    13. Localization of dynamin 2 in rat seminiferous tubules during the spermatogenic cycle. PMID: 12199526
    14. there is a distinct signaling network originating from the dopamine receptor that regulates the state of dynamin-2 phosphorylation and that promotes its location at the site of Na(+),K(+)-ATPase endocytosis PMID: 12205083
    15. The dynamins comprise a large family of mechanoenzymes known to participate in membrane modeling events. All three conventional dynamin genes (Dnm1, Dnm2, Dnm3) are expressed in mammalian brain and produce more than 27 different dynamin proteins. PMID: 12646135
    16. dynamin plays role in Rac trafficking to allow for lamellipodia formation and cell spreading PMID: 14617821
    17. Src-mediated phosphorylation of dynamin-2 is an essential requirement for scission of caveolae and the resultant transendothelial transport of albumin PMID: 15007081
    18. the first demonstration of the co-expression of all three dynamin isoforms in a non-tumor cell PMID: 15126636
    19. differential binding of SH3 domain-containing proteins to dynamin-1 and -2 may contribute to the distinct functions performed by these isoforms PMID: 15834155
    20. Data show that swapping the highly homologous GTPase domain of dynamin-2 into dynamin-1 is sufficient to confer caspase-3 activation. PMID: 16938290
    21. Dnm2 mediates fluid-phase micropinocytosis in epithelial cells. PMID: 18003703
    22. cooperative function of dynamin 2 and amphiphysin 1 in phosphatidylserine-dependent phagocytosis is strongly suggested in sertoli cells PMID: 19122684
    23. Dynamin2 GTPase and cortactin remodel actin filaments. PMID: 19605363

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cell junction. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Midbody. Membrane, clathrin-coated pit. Cell projection, phagocytic cup. Cytoplasmic vesicle, phagosome membrane; Peripheral membrane protein.; [Isoform 2]: Cytoplasmic vesicle, clathrin-coated vesicle. Membrane, clathrin-coated pit.; [Isoform 4]: Cell membrane.
  • 蛋白家族：
    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family
  • 組織特異性：
    Ubiquitously expressed. Brain expression is restricted to glial cells and fibroblasts. Highest levels in the testis.
  • 數據庫鏈接：


主站蜘蛛池模板： 国产精品边做奶水狂喷无码| 狠狠色综合网站久久久久久久高清| 性xxxxx大片免费视频| 久久久精品2019免费观看| 亚洲中文久久精品无码1| 色婷婷综合久久久中文字幕 | 人禽伦免费交视频播放| 久久久婷婷五月亚洲97号色| 成人国产片视频在线观看| 丰满无码人妻热妇无码区| 国产三级在线观看完整版| 中文字幕一区二区三区日韩精品| 成在人线av无码免费高潮喷水 | 色婷婷五月综合欧美图片| 天堂无码人妻精品av一区| 无码少妇精品一区二区免费| 成在人线av无码免费高潮水老板| 久久大香线蕉国产精品免费| 国产精品一区二区无线| 国产欧美另类久久精品蜜芽| 人人妻人人爽人人做夜欢视频九色| 亚洲无碼网站观看| 久久久精品国产免大香伊| 亚洲国产成人久久综合三区| 中文字幕 欧美精品 第1页| 国产精品无码一区二区三区在| 欧美 国产 综合 欧美 视频| 无码手机线免费观看| 国产亚洲精品久久77777| 麻豆高清免费国产一区| 在线观看片免费人成视频播放| 岛国在线无码高清视频| 国产午夜福利视频在线观看| 中文字幕无码日韩专区免费| av无码久久久精品免费| 欧美情侣性视频| 51国产黑色丝袜高跟鞋| 乱中年女人伦av二区| 国产精品久久久久久久久绿色| 国产av无码专区亚洲awww| 秋秋影视午夜福利高清|