在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Complement component 1 Q subcomponent-binding protein, mitochondrial (C1qbp)

Recombinant Rat Complement component 1 Q subcomponent-binding protein, mitochondrial (C1qbp)

  • 中文名稱：
    Recombinant Rat Complement component 1 Q subcomponent-binding protein, mitochondrial(C1qbp)
  • 貨號：
    CSB-YP003639RA
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat Complement component 1 Q subcomponent-binding protein, mitochondrial(C1qbp)
  • 貨號：
    CSB-EP003639RA
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat Complement component 1 Q subcomponent-binding protein, mitochondrial(C1qbp)
  • 貨號：
    CSB-EP003639RA-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat Complement component 1 Q subcomponent-binding protein, mitochondrial(C1qbp)
  • 貨號：
    CSB-BP003639RA
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat Complement component 1 Q subcomponent-binding protein, mitochondrial(C1qbp)
  • 貨號：
    CSB-MP003639RA
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    C1qbp
  • Uniprot No.：
  • 別名：
    C1qbp; Gc1qbpComplement component 1 Q subcomponent-binding protein; mitochondrial; GC1q-R protein; Glycoprotein gC1qBP; C1qBP
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    72-279
  • 氨基酸序列
    LHTEGDKAF VEFLTDEIKE EKKIQKHKSL PKMSGDWELE VNGTEAKLLR KVAGEKITVT FNINNSIPPT FDGEEEPSQG QKAEEQEPEL TSTPNFVVEV TKTDGKKTLV LDCHYPEDEI GHEDEAESDI FSIKEVSFQT TGDSEWRDTN YTLNTDSLDW ALYDHLMDFL ADRGVDNTFA DELVELSTAL EHQEYITFLE DLKSFVKSQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Is believed to be a multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, protein synthesis in mitochondria, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing. At the cell surface is thought to act as an endothelial receptor for plasma proteins of the complement and kallikrein-kinin cascades. Putative receptor for C1q; specifically binds to the globular 'heads' of C1q thus inhibiting C1; may perform the receptor function through a complex with C1qR/CD93. In complex with cytokeratin-1/KRT1 is a high affinity receptor for kininogen-1/HMWK. Can also bind other plasma proteins, such as coagulation factor XII leading to its autoactivation. May function to bind initially fluid kininogen-1 to the cell membrane. The secreted form may enhance both extrinsic and intrinsic coagulation pathways. It is postulated that the cell surface form requires docking with transmembrane proteins for downstream signaling which might be specific for a cell-type or response. By acting as C1q receptor is involved in chemotaxis of immature dendritic cells and neutrophils and is proposed to signal through CD209/DC-SIGN on immature dendritic cells, through integrin alpha-4/beta-1 during trophoblast invasion of the decidua, and through integrin beta-1 during endothelial cell adhesion and spreading. Signaling involved in inhibition of innate immune response is implicating the PI3K-AKT/PKB pathway. Required for protein synthesis in mitochondria. In mitochondrial translation may be involved in formation of functional 55S mitoribosomes; the function seems to involve its RNA-binding activity. May be involved in the nucleolar ribosome maturation process; the function may involve the exchange of FBL for RRP1 in the association with pre-ribosome particles. Involved in regulation of RNA splicing by inhibiting the RNA-binding capacity of SRSF1 and its phosphorylation. Is required for the nuclear translocation of splicing factor U2AF1L4. Involved in regulation of CDKN2A- and HRK-mediated apoptosis. May be involved in regulation of FOXC1 transcriptional activity and NFY/CCAAT-binding factor complex-mediated transcription. May play a role in antibacterial defense.
  • 基因功能參考文獻：
    1. Data indicate that disrupted ovarian hyaluronan binding protein 1 (HABP1) along with concurrent altered expression and hyperactivation of related MMPs can lead to abnormal follicular maturation resulting into ovarian dysfunction in polycystic ovary (PCO). PMID: 25300617
    2. findings indicate a possible role for HABP1 proprotein in apoptosis induction of germ cells in the cryptorchid testes PMID: 21311052
    3. The present study provides evidence of the ability of soluble gC1qR to enhance S. aureus-fibrinogen interactions via simultaneously binding fibrinogen and S. aureus in a S. aureus endocarditis model. [gClqR/p33] PMID: 16861627
    4. Stage-specific expression of proprotein form of hyaluronan binding protein 1 (HABP1) during spermatogenesis in rat. PMID: 11984833
    5. Rat and mouse homologs of the HABP1 pseudogene also contain multiple mutations, leading to the insertion of premature stop codons confirming the identity of a processed pseudogene. PMID: 12443542
    6. These studies suggest that gC1qR interacts specifically with alpha1B- and alpha1D-, but not alpha1A-ARs, and this interaction depends on the presence of an intact C-tail [gC1qR]. PMID: 14626446
    7. these findings demonstrate the appearance of HABP1 proprotein in the pachytene spermatocytes and the round spermatids during the initial stages of postnatal testis development and suggest that this expression may be crucial for spermatogenesis. PMID: 16582418

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion matrix. Nucleus. Cell membrane; Peripheral membrane protein; Extracellular side. Secreted. Cytoplasm. Nucleus, nucleolus.
  • 蛋白家族：
    MAM33 family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 囯产精品一区二区三区线| 99久久国产露脸精品| 未满十八18禁止午夜免费网站 | 国产亚洲精品第一综合另类 | 精品国产三级a∨在线欧美| 亚洲精品久久国产精品| 熟睡人妻被讨厌的公侵犯深田咏美| 人妻 校园 激情 另类| 日本丰满护士爆乳xxxx| 久久久久久亚洲精品成人| 国产人妻精品一区二区三区| 久久亚洲国产成人精品无码区| 成人av一本不卡二卡| 色综合亚洲一区二区小说| 色喜国模李晴超大尺度| 久久综合九色综合97欧美| 久久丫精品系列| 成熟丰满熟妇高潮xxxxx| 男女超爽视频免费播放| 亚洲性夜夜综合久久7777| 精品国产一区二区三区av色诱 | 国产乱理伦片在线观看| 欧美一区二区| 亚洲色一色噜一噜噜噜| 96亚洲精华国产精华精华液| 99久久99久久精品国产片果冻| 国产一区二区在线影院| 久久99精品国产99久久6| 成视频年人黄网站免费视频| 69精品人人人人| 五月丁香六月激情综合在线视频 | 日韩一区二区三免费高清| 国产狂喷潮在线观看| 亚洲熟妇久久精品| 国产97公开成人免费视频在线观看 | 免费女人高潮流视频在线| 日韩一区二区三区精品| 国产成人8x人在线视频软件 | 一个人看的免费视频www中文字幕| 亚洲字幕av一区二区三区四区| 国产欧美日韩一区2区|