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  4. Recombinant Rat Collagen alpha-1 (III) chain (Col3a1), partial

Recombinant Rat Collagen alpha-1 (III) chain (Col3a1), partial

  • 中文名稱：
    Recombinant Rat Collagen alpha-1(III) chain(Col3a1) ,partial
  • 貨號：
    CSB-YP005740RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat Collagen alpha-1(III) chain(Col3a1) ,partial
  • 貨號：
    CSB-EP005740RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat Collagen alpha-1(III) chain(Col3a1) ,partial
  • 貨號：
    CSB-EP005740RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat Collagen alpha-1(III) chain(Col3a1) ,partial
  • 貨號：
    CSB-BP005740RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat Collagen alpha-1(III) chain(Col3a1) ,partial
  • 貨號：
    CSB-MP005740RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Col3a1Collagen alpha-1(III) chain
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
  • 基因功能參考文獻：
    1. miR-let-7b and COL3A1 might play critical roles in neuronal injury, they are potential therapeutic targets. PMID: 28436683
    2. High Collagen Type III expression is associated with renal fibrosis in experimental kidney diseases. PMID: 25784725
    3. The regulatory effect of melatonin (MLT)cannot be explained by its effect on procollagen gene expression, since neither MLT nor pinealectomy has an influence on alpha1 (I) and alpha1 (III) procollagen mRNA content in the scar. PMID: 20388018
    4. mRNa expression of Col3a1 increases in kidney and decreases in heart under hyperglycaemic/hyperinsulinaemic conditions. PMID: 20836762
    5. Diminution of collagen type III cortical domain with trabecular atrophy suggests that it has a proactive or reactive role in determining bone mass and strength by facilitating musculoskeletal exchange in a form that is disengaged by ovariectomy. PMID: 12810172
    6. In cortical bone a prominent discrete subperiosteal domain becomes wider with exercise and contains more numerous collagen III (CIII)-stained fibers, evidence that short-term voluntary exercise augments both cortical and cancellous microarchitecture. PMID: 12810173
    7. Quinapril treatment reduced the levels of Col3a1 mRNA in congestive myopathic rats. PMID: 14575307

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  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Fibrillar collagen family
  • 數據庫鏈接：


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