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Recombinant Rat Calcineurin-binding protein cabin-1 (Cabin1), partial

  • 中文名稱:
    Recombinant Rat Calcineurin-binding protein cabin-1(Cabin1) ,partial
  • 貨號:
    CSB-YP004384RA
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Rat Calcineurin-binding protein cabin-1(Cabin1) ,partial
  • 貨號:
    CSB-EP004384RA
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Rat Calcineurin-binding protein cabin-1(Cabin1) ,partial
  • 貨號:
    CSB-EP004384RA-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Rat Calcineurin-binding protein cabin-1(Cabin1) ,partial
  • 貨號:
    CSB-BP004384RA
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Rat Calcineurin-binding protein cabin-1(Cabin1) ,partial
  • 貨號:
    CSB-MP004384RA
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Cabin1Calcineurin-binding protein cabin-1; Calcineurin inhibitor; CAIN
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin.
  • 基因功能參考文獻(xiàn):
    1. Knocking down Cabin1 induces the disruption of cytoskeleton and mitochondrial dysfunction in podocyte. Cabin1 could be a crucial factor in podocyte damage. PMID: 29368245
    2. Injury to renal tubular epithelial cells results in up-regulation of cabin1 expression. PMID: 29190603
    3. In conclusion, Cabin1 expression significantly increases during podocyte injury. Knockdown of Cabin1 induces p53 expression decrease in cultured podocyte. Cabin1 may provide a new target to investigate podocyte injury. PMID: 26400065
  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm.
  • 組織特異性:
    Widely expressed with prominent expression in neurons.
  • 數(shù)據(jù)庫鏈接:

    KEGG: rno:94165

    STRING: 10116.ENSRNOP00000001659

    UniGene: Rn.4



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