在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Breast cancer anti-estrogen resistance protein 1 (Bcar1), partial

  • 中文名稱:
    Recombinant Rat Breast cancer anti-estrogen resistance protein 1(Bcar1) ,partial
  • 貨號(hào):
    CSB-YP733970RA
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Rat Breast cancer anti-estrogen resistance protein 1(Bcar1) ,partial
  • 貨號(hào):
    CSB-EP733970RA
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Rat Breast cancer anti-estrogen resistance protein 1(Bcar1) ,partial
  • 貨號(hào):
    CSB-EP733970RA-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Rat Breast cancer anti-estrogen resistance protein 1(Bcar1) ,partial
  • 貨號(hào):
    CSB-BP733970RA
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Rat Breast cancer anti-estrogen resistance protein 1(Bcar1) ,partial
  • 貨號(hào):
    CSB-MP733970RA
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Bcar1; Cas; CrkasBreast cancer anti-estrogen resistance protein 1; CRK-associated substrate; p130cas
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. Implicated in induction of cell migration and cell branching. Involved in the BCAR3-mediated inhibition of TGFB signaling.
  • 基因功能參考文獻(xiàn):
    1. Cas plays pivotal roles in liver development through the reorganization of the actin cytoskeleton and formation of fenestrae in sinusoidal endothelial cells. PMID: 20623582
    2. Analysis of protein domains of Cas protein in rat. PMID: 12011056
    3. degradation of p130cas during apoptosis is modulated in a phosphorylation-dependent manner PMID: 12480533
    4. in cells transformed by the v-crk oncogene, the adapter protein Cas forms a stable complex with the p85 regulatory subunit of phosphatidylinositol 3'-kinase (PI3K) coincident with the appearance of Cas-associated PI3K activity PMID: 12692262
    5. upregulation of PTP-PEST is both necessary and sufficient to explain NO-induced p130cas dephosphorylation in vascular smooth muscle PMID: 12714323
    6. tyrosine phosphorylation of Crk-associated substrate in pancreatic beta-cells is stimulated by glucose PMID: 12746446
    7. glutamic acid mutation of tyrosine 635 makes SHEP1 unable to promote Cas-Crk association, membrane ruffling, and cell migration toward epidermal growth factor (EGF), implying that these activities of SHEP1 depend upon a physical interaction with Cas PMID: 15272013
    8. functional domain analysis of the docking protein p130Cas PMID: 15485652
    9. the solution structure shows that the p130cas serine-rich domain is a four-helix bundle PMID: 15795225
    10. Data suggest that IGF-I induces smooth muscle cell motility by increasing phosphotyrosine levels of p130(cas) and activating Rac1, and that nitric oxide decreases motility by activating PTP-PEST. PMID: 16354758
    11. These data are the first to implicate Crk-associated substrate in the signal transduction of 5-HT. PMID: 16861698
    12. Abl may play a pivotal role in mediating CAS phosphorylation, the assembly of the multiprotein complex, actin assembly, and constriction in resistance arteries PMID: 17615370
    13. Caspase-mediated cleavage of p130Cas generates a 31 kDa fragment, inhibits p21Cip1 transcription and acts as an amplifier of apoptotic signalling PMID: 17617061

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell junction, focal adhesion. Cytoplasm. Cell projection, axon.
  • 蛋白家族:
    CAS family
  • 組織特異性:
    Widely expressed. Higher expression in lung, intestine and testis.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 亚洲图片综合图区20p| 国产精品无码a∨精品影院app| 午夜国人精品av免费看| 无码人妻专区免费视频| 亚洲狠狠婷婷综合久久久久图片| 可以直接看的无码av| 久久中文字幕人妻av熟女| 国产精品一卡二卡三卡| 无码孕妇孕交在线观看| 亚洲国产婷婷六月丁香| 大桥未久亚洲一区二区 | 亚洲精品久久av无码一区二区| 国产高清国产精品国产专区| 又粗又硬又大又爽免费视频播放| 黑巨人与欧美精品一区| 黑人强伦姧人妻久久| 久久久久国产精品人妻aⅴ果冻| 欧美偷窥清纯综合图区| 无码国产欧美一区二区三区不卡| 欧美孕妇xxxx做受欧美88| 国精产品一区一区三区| 老外和中国女人毛片免费视频| 久久久喷潮一区二区三区| 人人超碰人人超级碰国| 无码h肉动漫在线观看| 情欲少妇人妻100篇| 欧美另类又黄又爽的a片| 久久av无码精品人妻系列试探| 亚洲综合av永久无码精品一区二区| av无码人妻一区二区三区牛牛 | 97在线精品视频免费| 久久久久久无码精品人妻a片软件| 丰满熟妇人妻av无码区| 欧美性videos高清精品| 99久热re在线精品视频| 国产精品久久久久影院亚瑟| 免费精品国产人妻国语| 中文字幕婷婷日韩欧美亚洲| 久久只精品99品免费久23| 无套内内射视频网站| 国内精品久久久久久久久齐齐|