在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (Plce1), partial

Recombinant Rat 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (Plce1), partial

  • 中文名稱：
    大鼠Plce1重組蛋白
  • 貨號：
    CSB-YP858169RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Plce1重組蛋白
  • 貨號：
    CSB-EP858169RA
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Plce1重組蛋白
  • 貨號：
    CSB-EP858169RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Plce1重組蛋白
  • 貨號：
    CSB-BP858169RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Plce1重組蛋白
  • 貨號：
    CSB-MP858169RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Plce1; Plce; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1; EC 3.1.4.11; Phosphoinositide phospholipase C-epsilon-1; Phospholipase C-epsilon-1; PLC-epsilon-1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation. In podocytes, is involved in the regulation of lamellipodia formation. Acts downtream of AVIL to allow ARP2/3 complex assembly.
  • 基因功能參考文獻：
    1. These results provide first evidence that Gbetagamma directly interacts with PLC and yield insights into the mechanism by which betagamma subunits activate PLC. PMID: 29535186
    2. results have shown a novel role of PLCepsilon in the maintenance of endothelial barrier function, via its CDC25 GEF domain and lipase activity, and subsequent up-regulation of Rap1 activity PMID: 27612188
    3. Phospholipase C epsilon scaffolds to muscle-specific A kinase anchoring protein (mAKAPbeta) and integrates multiple hypertrophic stimuli in cardiac myocytes. PMID: 21550986
    4. Results indicate that phospholipase Cepsilon is a direct downstream effector for RhoA and that RhoA-dependent activation of PLC-epsilon depends on a unique insert within the catalytic core of the phospholipase. PMID: 15322077
    5. PLC epsilon down-regulates regulation of integrin activation via an independent H-ras signaling pathway. PMID: 16895916
    6. PLC-epsilon can be directly and concomitantly activated by both RhoA and individual Ras GTPases resulting in diverse upstream control of signaling cascades downstream of PLC-epsilon PMID: 18765661

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytosol. Cell membrane. Golgi apparatus membrane. Cell projection, lamellipodium.
  • 組織特異性：
    Ubiquitously expressed. Detected in glomerular podocytes (at protein level).
  • 數據庫鏈接：


主站蜘蛛池模板： 成人无码视频| 亚洲色无码中文字幕手机在线| 老汉老妇姓交视频| 国产精品视频免费一区二区| 国产精品久久久久9999爆乳| 亚洲国产av无码精品无广告 | 午夜影视免费| 丰腴饱满的极品熟妇| 日韩精品无码成人专区| 99久久国产成人免费网站| 午夜精品久久久久久久99老熟妇 | 中文字幕aⅴ人妻一区二区| 国产成人综合色视频精品| 日韩人妻无码精品二专区| 内射人妻无码色ab麻豆| 国产麻豆精品一区二区三区v视界| 色综合av男人的天堂伊人| 成人自慰女黄网站免费大全| 欧美人成精品网站播放| 曰韩人妻无码一区二区三区综合部| 亚洲国产成人精品久久久| 69成人免费视频无码专区| 久久精品亚洲综合专区| 久久综合给合久久狠狠狠97色| 久99久无码精品视频免费播放| 亚洲成片在线观看12345| 国产精品禁18久久久夂久| 日日噜噜夜夜狠狠va视频v| 国内精品卡一卡二卡三| 国产免费人成网站x8x8| 中文字幕被公侵犯的漂亮人妻 | 欧美日韩一卡2卡三卡4卡 乱码欧美孕交 | 久久精品无码一区二区三区| 麻豆果冻精东九一传媒mv| 亚洲成aⅴ人片在线观| 成人天堂资源www在线| 亚洲欧美日韩综合在线一| 欧美日韩视频在线第一区| 黄a大片av永久免费| 久久/这里只精品热在线获取| 亚洲欧美成αⅴ人在线观看|