Recombinant Rabbit Serum paraoxonase/arylesterase 1 (PON1)

中文名稱：

小圓錐花果PON1重組蛋白
貨號：

CSB-YP018369RB
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小圓錐花果PON1重組蛋白
貨號：

CSB-EP018369RB
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小圓錐花果PON1重組蛋白
貨號：

CSB-EP018369RB-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小圓錐花果PON1重組蛋白
貨號：

CSB-BP018369RB
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小圓錐花果PON1重組蛋白
貨號：

CSB-MP018369RB
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

PON1
Uniprot No.：

P27170
別名：

PON1; PON; Serum paraoxonase/arylesterase 1; PON 1; EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; Aromatic esterase 1; A-esterase 1; Serum aryldialkylphosphatase 1
種屬：

Oryctolagus cuniculus (Rabbit)
蛋白長度：

Full Length of Mature Protein
表達(dá)區(qū)域：

2-359
氨基酸序列

AKLTALTLL GLGLALFDGQ KSSFQTRFNV HREVTPVELP NCNLVKGIDN GSEDLEILPN GLAFISAGLK YPGIMSFDPD KPGKILLMDL NEKDPVVLEL SITGSTFDLS SFNPHGISTF TDEDNIVYLM VVNHPDSKST VELFKFQEKE KSLLHLKTIR HKLLPSVNDI VAVGPEHFYA TNDHYFIDPY LKSWEMHLGL AWSFVTYYSP NDVRVVAEGF DFANGINISP DGKYVYIAEL LAHKIHVYEK HANWTLTPLK SLDFNTLVDN ISVDPVTGDL WVGCHPNGMR IFYYDPKNPP ASEVLRIQDI LSKEPKVTVA YAENGTVLQG STVAAVYKGK MLVGTVFHKA LYCELSQAN
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.
基因功能參考文獻(xiàn)：
1. ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL paraoxonase activity PMID: 20221865
2. PON1 can decrease the AChE inhibition, and alleviated clinical signs and tissue damage caused by dichlorvos. PMID: 20412842
亞細(xì)胞定位：

Secreted, extracellular space.
蛋白家族：

Paraoxonase family
組織特異性：

Plasma. Associated with HDL.
數(shù)據(jù)庫鏈接：

KEGG: ocu:100009133

STRING: 9986.ENSOCUP00000004445

UniGene: Ocu.1952