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  4. Recombinant Rabbit Metalloproteinase inhibitor 1 (TIMP1)

Recombinant Rabbit Metalloproteinase inhibitor 1 (TIMP1)

  • 中文名稱：
    小圓錐花果TIMP1重組蛋白
  • 貨號：
    CSB-YP023560RB
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小圓錐花果TIMP1重組蛋白
  • 貨號：
    CSB-EP023560RB
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小圓錐花果TIMP1重組蛋白
  • 貨號：
    CSB-EP023560RB-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小圓錐花果TIMP1重組蛋白
  • 貨號：
    CSB-BP023560RB
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小圓錐花果TIMP1重組蛋白
  • 貨號：
    CSB-MP023560RB
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    TIMP1; Metalloproteinase inhibitor 1; Tissue inhibitor of metalloproteinases 1; TIMP-1
  • 種屬：
    Oryctolagus cuniculus (Rabbit)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    24-207
  • 氨基酸序列
    CTCVPPH PQTAFCNSDL VIRAKFVGAP EVNHTTLYQR YEIKTTKMFK GFDALGHATD IRFVYTPAME SVCGYSHKSQ NRSEEFLIAG QLRNGLLHIT TCSFVVPWNS LSFSQRSGFT KTYAAGCDMC TVFACASIPC HLESDTHCLW TDQLLLGSDK GFQSRHLACL PQEPGLCAWQ SLRPRKD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.
  • 基因功能參考文獻：
    1. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2, MMP-9 and TIMP-1 in rabbits with acute paraquat poisoning. PMID: 22801080
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Protease inhibitor I35 (TIMP) family
  • 數據庫鏈接：


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