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  4. Recombinant Rabbit Arginase-2, mitochondrial (ARG2)

Recombinant Rabbit Arginase-2, mitochondrial (ARG2)

  • 中文名稱：
    Recombinant Rabbit Arginase-2, mitochondrial(ARG2)
  • 貨號：
    CSB-YP709291RB
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rabbit Arginase-2, mitochondrial(ARG2)
  • 貨號：
    CSB-EP709291RB
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rabbit Arginase-2, mitochondrial(ARG2)
  • 貨號：
    CSB-EP709291RB-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rabbit Arginase-2, mitochondrial(ARG2)
  • 貨號：
    CSB-BP709291RB
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rabbit Arginase-2, mitochondrial(ARG2)
  • 貨號：
    CSB-MP709291RB
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    ARG2; Arginase-2; mitochondrial; EC 3.5.3.1; Arginase II; Type II arginase
  • 種屬：
    Oryctolagus cuniculus (Rabbit)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    23-354
  • 氨基酸序列
    VHSVAVIG APFSQGQKRK GVECGPAAIR DAGLVKRLSD LGCRLKDYGD LSFTPVPKDD LYNNLIVNPR SVGLANQELA EVVNRAVSGG YSCVTVGGDH SLAIGTISGH ARHCPDLCVV WVDAHADINT PLTTSSGNLH GQPVSFLLRE LQDKVPQLPG FSWIKPCISS PSIVYIGLRD VDPPEHFILK KYDIQYFSMR DIDRLGIQKV MEQTFDLLIG KKQRPIHLSF DIDAFDPTLA PATGTPGCGG ADLSRRMYIS EEIHNTGLLS ALDLVEVNPR LAASDEEAKA TASLAVDVIA SSFGQTREGG HTVYEQLPPP SSPHESENAE RVRI
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signaling, which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction. Can inhibit endothelial autophagy independently of its enzymatic activity implicating mTORC2 signaling. Involved in vascular smooth muscle cell senescence and apoptosis independently of its enzymatic activity.
  • 基因功能參考文獻(xiàn)：
    1. Kidneys from circulation-restricted fetuses showed arginase-2 protein induction. PMID: 27109011
    2. In heart failure, increased iNOS and arginase II expression results in unchanged NO species and protein S-nitrosylation; with substrate limitation, uncoupled iNOS produces superoxide anions and contributes to contractile dysfunction. PMID: 20511413
  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    Arginase family
  • 數(shù)據(jù)庫鏈接：


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