在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human papillomavirus 33 Protein E6 (E6)

  • 中文名稱:
    Recombinant Human papillomavirus 33 Protein E6 (E6)
  • 貨號:
    CSB-YP361821HNF
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human papillomavirus 33 Protein E6 (E6)
  • 貨號:
    CSB-EP361821HNF
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human papillomavirus 33 Protein E6 (E6)
  • 貨號:
    CSB-EP361821HNF-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human papillomavirus 33 Protein E6 (E6)
  • 貨號:
    CSB-BP361821HNF
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human papillomavirus 33 Protein E6 (E6)
  • 貨號:
    CSB-MP361821HNF
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    E6Protein E6
  • 種屬:
    Human papillomavirus type 33
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-149
  • 氨基酸序列
    MFQDTEEKPR TLHDLCQALE TTIHNIELQC VECKKPLQRS EVYDFAFADL TVVYREGNPF GICKLCLRFL SKISEYRHYN YSVYGNTLEQ TVKKPLNEIL IRCIICQRPL CPQEKKRHVD LNKRFHNISG RWAGRCAACW RSRRRETAL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    This protein may be involved in the oncogenic potential of this virus (cervical neoplasia-associated virus).; Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT). The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization. Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis. E6 also inhibits immune response by interacting with host IRF3 and TYK2. These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway.
  • 亞細胞定位:
    Host cytoplasm. Host nucleus.
  • 蛋白家族:
    Papillomaviridae E6 protein family


主站蜘蛛池模板: 人成午夜大片免费视频| 暖暖 免费 高清 日本 在线| 国产精自产拍在线看中文| 麻花豆传媒剧国产免费mv观看| 色婷婷香蕉在线一区二区| 久久综合九色欧美综合狠狠| 亚洲美女国产精品久久久久久久久| 最近最好的中文字幕2019免费| 久久精品国产69国产精品亚洲| 少妇精品无码一区二区三区| 婷婷五月深爱综合开心网| 成人亚洲欧美激情在线电影| 鲁大师在线视频播放免费观看| 久久国产劲暴∨内射新川| 中文字幕漂亮人妻熟睡中被公侵犯| 射精区-区区三区| 国产精品极品美女自在线观看免费| 中文字幕av伊人av无码av| 亚洲 制服丝袜 中文字幕 在线| 欧洲人妻丰满av无码久久不卡| 国产另类ts人妖一区二区| 久久亚洲精品成人av二次元| 欧美两根一起进3p在线观看| 国内老熟妇对白xxxxhd| 亚洲中文字幕无码mv| 一本无码中文字幕在线观| 久久人人爽人人爽人人片av高清| 欧美老肥妇做爰bbww| 乱中年女人伦av二区| 国产aⅴ夜夜欢一区二区三区| 国产妇女馒头高清泬20p多毛| 日日躁狠狠躁狠狠爱| 国产剧情无码播放在线看| 日韩国产成人无码av毛片| 国产在线精品99一卡2卡| 久热爱精品视频线路一| 天堂www中文在线资源| 天干夜啦天干天干国产免费| 偷自拍亚洲视频在线观看99| 国产卡一卡二卡三| 樱花草在线社区www韩国|