在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human papillomavirus type 70 Protein E6 (E6)

  • 中文名稱:
    Recombinant Human papillomavirus type 70 Protein E6(E6)
  • 貨號:
    CSB-YP343102HOQ
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human papillomavirus type 70 Protein E6(E6)
  • 貨號:
    CSB-EP343102HOQ
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human papillomavirus type 70 Protein E6(E6)
  • 貨號:
    CSB-EP343102HOQ-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human papillomavirus type 70 Protein E6(E6)
  • 貨號:
    CSB-BP343102HOQ
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human papillomavirus type 70 Protein E6(E6)
  • 貨號:
    CSB-MP343102HOQ
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    E6; Protein E6
  • 種屬:
    Human papillomavirus type 70
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-158
  • 氨基酸序列
    MARFPNPAER PYKLPDLCTA LDTTLHDITI DCVYCKTQLQ QTEVYEFAFS DLFIVYRNGE PYAACQKCIK FHAKVRELRH YSNSVYATTL ESITNTKLYN LSIRCMSCLK PLCPAEKLRH VNTKRRFHQI AGSYTGQCRH CWTSNREDRR RIRRETQV
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT). The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization. Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis. E6 also inhibits immune response by interacting with host IRF3 and TYK2. These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway.
  • 亞細胞定位:
    Host cytoplasm. Host nucleus.
  • 蛋白家族:
    Papillomaviridae E6 protein family


主站蜘蛛池模板: 亚洲国产av一区二区三区四区| 人人玩人人添人人澡| 影音先锋日日狠狠久久| 任我橹这里只有精品 在线视频| 人人狠狠综合久久亚洲爱咲| 精品成人av一区二区三区| 99久久人妻精品免费二区| 久久人人做人人妻人人玩精品hd| 乱人伦无码中文视频在线| 国精品人妻无码一区二区三区蜜柚| 亚洲人成网站18禁止一区| 人妻熟女一区二区aⅴ千叶宁真| 人妻人人做人做人人爱| 51社区精品视频| 日日摸夜夜摸狠狠摸婷婷| 少妇富婆高级按摩出水高潮| 欧美性色19p| 麻豆精品一区二区综合av| 欧美人与动牲交zooz乌克兰| 精品一区二区国产在线观看| 永久免费无码av在线网站| 国产亚洲精品美女久久久| 久久久精品午夜免费不卡| 亚洲色无码专区在线观看精品| 国产色青青视频在线观看撒| 亚洲国产aⅴ综合网| 国产欧美性成人精品午夜| 丰满少妇弄高潮了www| 国产精品卡1卡2卡三卡四| 中国凸偷窥xxxx自由视频| 精品人妻少妇一区二区三区| 99精品一区二区三区无码吞精| 午夜福利啪啪无遮挡免费| 成 人 网 站 免费 在线| 国产精品欧美久久久久久日本一道| 亚洲人成在线观看网站不卡| 天堂va欧美ⅴa亚洲va| 久久99精品九九九久久婷婷| 欧美最猛黑人xxxx| 做爰高潮视频免费的看| 中文字幕av无码免费一区|