在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Probable serine/threonine-protein kinase zyg-1 (zyg-1), partial

Recombinant Probable serine/threonine-protein kinase zyg-1 (zyg-1), partial

  • 中文名稱：
    秀麗隱桿線蟲zyg-1重組蛋白
  • 貨號：
    CSB-YP872406CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲zyg-1重組蛋白
  • 貨號：
    CSB-EP872406CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲zyg-1重組蛋白
  • 貨號：
    CSB-EP872406CXY-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲zyg-1重組蛋白
  • 貨號：
    CSB-BP872406CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲zyg-1重組蛋白
  • 貨號：
    CSB-MP872406CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    zyg-1
  • Uniprot No.：
  • 別名：
    zyg-1; F59E12.2Probable serine/threonine-protein kinase zyg-1; EC 2.7.11.1; Zygote defective protein 1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Protein kinase that plays a central role in centrosome duplication, control of centrosome size, spindle formation and nuclear envelope breakdown during cell divisions. Paternal copy is required to regulate synthesis of daughter centrioles prior to fertilization. Maternal copy regulates centrosome duplication during later cell cycles. Functions upstream of sas-5 and sas-6, and is required for their localization to the centrosome. Its role in nuclear envelope breakdown is mediated by the spindly-like protein spdl-1 and the RZZ complex, which in turn recruits the spindle checkpoint proteins mdf-1 and mdf-2, dynein and dynactin to unattached kinetochores.
  • 基因功能參考文獻：
    1. These findings lead us to conclude that ZYG-1 promotes limited centriole amplification solely during the symmetric division in the C. elegans seam lineage. PMID: 29307730
    2. Structure of the C. elegans ZYG-1 cryptic polo box suggests a conserved mechanism for centriolar docking of Plk4 kinases. PMID: 24980795
    3. Direct interactions of the SAS-6 coiled coil with ZYG-1 and SAS-5 are required to recruit SAS-6 to the mother centriole. PMID: 23673331
    4. Data show that levels of the C. elegans Plk4 homolog ZYG-1 are elevated by impairing proteasome or SCF function, indicating that ZYG-1 is regulated by a conserved mechanism. PMID: 22623721
    5. Data reveal differences in the regulation of mitotic and meiotic centrosome duplication, particularly with regard to ZYG-1 activity, and reveal an important role for centrosomes in spermatid formation. PMID: 20144993
    6. Study demonstrates that the kinase ZYG-1 phosphorylates the coiled-coil protein SAS-6 at serine 123 in vitro; this phosphorylation event is crucial for centriole formation in vivo. PMID: 20059959
    7. Numerous candidate regulators of centrosome duplication and regulatory mechanism involving factors that tether the centrosome to the nucleus, have been identified. PMID: 17446307
    8. SZY-20 opposes the Plk4-related kinase ZYG-1 to limit centrosome size PMID: 19081077

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Component of the centrosome (PubMed:11371350). Present at centrioles only immediately before their duplication (PubMed:11371350). Expression at centrosomes increases from prophase to anaphase during mitosis (PubMed:22623721).
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 亚洲日韩av无码| 人与嘼交av免费| 免费国精产品自偷自偷免费看| 欧美 国产 综合 欧美 视频 | 亚洲精品久久久久玩吗| 丁香激情综合久久伊人久久| 亚洲国产日韩精品一区二区三区| 国产熟女出轨做受的叫床声| 四虎永久在线精品免费视频观看| 国产 高清 无码 在线播放| 最新精品露脸国产在线| 亚洲a∨精品一区二区三区| 一个人看的免费高清www视频| 亚洲人成网站在线观看69影院| 国产精品久久久久久久久动漫 | 国产精品99久久久久久人| 亚洲一区二区三区av无码| 大帝av在线一区二区三区| 777yyy亚洲精品久久久| 精品人成视频免费国产| 中文字幕日韩人妻在线视频| 午夜dv内射一区区| 亚洲国产综合无码一区 | 动漫精品无码h在线观看| 久久精品九九亚洲精品天堂| 精品无码一区二区三区av| 97久久超碰国产精品2021| 日本不卡三区| 亚洲国产精品一区二区动图| 少妇无码av无码去区钱| 波多野结衣一区二区三区av高清 | 最新国产精品自在线观看| 又爽又黄又无遮挡网站| 人妻插b视频一区二区三区| 精品一区二区久久久久久久网站 | 国厂精品114福利电影免费| 蜜桃av麻豆av果冻传媒| 熟女内射v888av| 亚洲欧美日韩中文字幕在线一区| 2020久久天天躁狠狠躁夜夜| 亚洲bbw性色大片|