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Recombinant Pongo pygmaeus B-cell receptor CD22 (CD22)

  • 中文名稱:
    Recombinant Pongo pygmaeus B-cell receptor CD22(CD22)
  • 貨號:
    CSB-YP868228EXP
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Pongo pygmaeus B-cell receptor CD22(CD22)
  • 貨號:
    CSB-EP868228EXP
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Pongo pygmaeus B-cell receptor CD22(CD22)
  • 貨號:
    CSB-EP868228EXP-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Pongo pygmaeus B-cell receptor CD22(CD22)
  • 貨號:
    CSB-BP868228EXP
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Pongo pygmaeus B-cell receptor CD22(CD22)
  • 貨號:
    CSB-MP868228EXP
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    CD22; SIGLEC2B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2; Siglec-2; CD antigen CD22; Fragment
  • 種屬:
    Pongo pygmaeus (Bornean orangutan)
  • 蛋白長度:
    Extracellular domain
  • 表達區域:
    18-330
  • 氨基酸序列
    DSS KWAFEHPETL YAWEGACVWI PCTYRALDGA LESFILFHNP EYNKNTSKFD GTRLYESTKD GEVPSEQKRV QFLGDKSKNC TLSIHPVHVN DSGQLGLRME SKTEKWMERI HLNVSERPFP PHIQLPPEIQ ESQEVTLTCL LNFSCYGYPI QLQWFLEGVP VGQAAVNSTS LATKSVFTRS ELKFSPQWSH HGKIVTCQLH GADGKFLSND TVQLNVKHTP KLKIEVNPSD AIVREGDSVT MTCEVSSSNP KYTTVSWLKD GTPLKKQNAL MLTLQEVTKD QSGKYCCQVS NDVGPGRSEE VFLQVQYAPE
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling cascade key molecules.
  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family


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