在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Pongo abelii Kelch-like ECH-associated protein 1 (KEAP1), partial

Recombinant Pongo abelii Kelch-like ECH-associated protein 1 (KEAP1), partial

  • 中文名稱：
    波戈阿貝利KEAP1重組蛋白
  • 貨號：
    CSB-YP012147PYX
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    波戈阿貝利KEAP1重組蛋白
  • 貨號：
    CSB-EP012147PYX
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    波戈阿貝利KEAP1重組蛋白
  • 貨號：
    CSB-EP012147PYX-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    波戈阿貝利KEAP1重組蛋白
  • 貨號：
    CSB-BP012147PYX
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    波戈阿貝利KEAP1重組蛋白
  • 貨號：
    CSB-MP012147PYX
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    KEAP1Kelch-like ECH-associated protein 1
  • 種屬：
    Pongo abelii (Sumatran orangutan)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination. KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non-enzymatic covalent modifications of highly reactive cysteine residues in KEAP1, leading to inactivate the ubiquitin ligase activity of the BCR(KEAP1) complex, promoting NFE2L2/NRF2 nuclear accumulation and expression of phase II detoxifying enzymes. In response to selective autophagy, KEAP1 is sequestered in inclusion bodies following its interaction with SQSTM1/p62, leading to inactivation of the BCR(KEAP1) complex and activation of NFE2L2/NRF2. The BCR(KEAP1) complex also mediates ubiquitination of SQSTM1/p62, increasing SQSTM1/p62 sequestering activity and degradation. The BCR(KEAP1) complex also targets BPTF and PGAM5 for ubiquitination and degradation by the proteasome.
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 日韩 亚洲 欧美 国产 精品| 午夜福利视频极品国产83| 性无码专区一色吊丝中文字幕| 人妻.中文字幕无码| 好男人社区www在线观看| 欧美丰满熟妇bbbbbb| 天天做天天爱夜夜爽 | 99热亚洲色精品国产88| 四虎成人国产精品永久在线 | 中文字幕亚洲码在线| 国精产品一区二区三区有限公司| 国产乱人伦av在线无码| 日本三级吃奶头添泬| 国产女精品视频网站免费| 人澡人人澡人人澡欧美| 日韩av无码免费播放| 校园春色~综合网| 国产白嫩护士在线播放| 欧美成人无码a区视频在线观看| 4399理论片午午伦夜理片| 美女av一区二区三区| 国产成人影院一区二区三区| 成人欧美一区二区三区视频| 欧美牲交a欧美牲交| 亚洲国产午夜精品理论片| 日本少妇内射视频播放舔| 小泽玛利亚一区二区在线观看| 国产精品白丝喷水在线观看| 日韩精品无码一本二本三本| 国产成人av区一区二区三| 国产精品久久人妻无码| 爱做久久久久久| 硬了进去湿好大娇喘视频| 少妇爽到呻吟的视频| 中文字幕一区二区三区四区五区| 脱岳裙子从后面挺进去在线观看 | 香蕉蕉亚亚洲aav综合| 男女啪啪网站大全免费| 日韩乱码人妻无码超清蜜桃| 图片区小说区激情区偷拍区| 体验区试看120秒啪啪免费|