在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Pongo abelii Alpha-ketoglutarate-dependent dioxygenase FTO (FTO), partial

Recombinant Pongo abelii Alpha-ketoglutarate-dependent dioxygenase FTO (FTO), partial

  • 中文名稱：
    波戈阿貝利FTO重組蛋白
  • 貨號：
    CSB-YP719167PYX
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    波戈阿貝利FTO重組蛋白
  • 貨號：
    CSB-EP719167PYX
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    波戈阿貝利FTO重組蛋白
  • 貨號：
    CSB-EP719167PYX-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    波戈阿貝利FTO重組蛋白
  • 貨號：
    CSB-BP719167PYX
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    波戈阿貝利FTO重組蛋白
  • 貨號：
    CSB-MP719167PYX
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    FTO
  • Uniprot No.：
  • 別名：
    FTOAlpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; U6 small nuclear RNA; 2'-O-methyladenosine-N(6)-)-demethylase FTO; EC 1.14.11.-; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; EC 1.14.11.-; mRNA; 2'-O-methyladenosine-N(6)-)-demethylase FTO; m6A(m)-demethylase FTO; EC 1.14.11.-; mRNA N(6)-methyladenosine demethylase FTO; EC 1.14.11.53; tRNA N1-methyl adenine demethylase FTO; EC 1.14.11.-
  • 種屬：
    Pongo abelii (Sumatran orangutan)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    RNA demethylase that mediates oxidative demethylation of different RNA species, such as mRNAs, tRNAs and snRNAs, and acts as a regulator of fat mass, adipogenesis and energy homeostasis. Specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. M6A demethylation by FTO affects mRNA expression and stability. Also able to demethylate m6A in U6 small nuclear RNA (snRNA). Mediates demethylation of N(6),2'-O-dimethyladenosine cap (m6A(m)), by demethylating the N(6)-methyladenosine at the second transcribed position of mRNAs and U6 snRNA. Demethylation of m6A(m) in the 5'-cap by FTO affects mRNA stability by promoting susceptibility to decapping. Also acts as a tRNA demethylase by removing N(1)-methyladenine from various tRNAs. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Also able to repair alkylated DNA and RNA by oxidative demethylation: demethylates single-stranded RNA containing 3-methyluracil, single-stranded DNA containing 3-methylthymine and has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Ability to repair alkylated DNA and RNA is however unsure in vivo. Involved in the regulation of fat mass, adipogenesis and body weight, thereby contributing to the regulation of body size and body fat accumulation. Involved in the regulation of thermogenesis and the control of adipocyte differentiation into brown or white fat cells. Regulates activity of the dopaminergic midbrain circuitry via its ability to demethylate m6A in mRNAs.
  • 亞細胞定位：
    Nucleus. Nucleus speckle. Cytoplasm.
  • 蛋白家族：
    Fto family
  • 數據庫鏈接：


主站蜘蛛池模板： 国产精品宾馆在线精品酒店| 国产日产亚洲系列最新| 亚洲欧洲免费无码| 人妻在客厅被c的呻吟| 久久精品99av高久久精品| 肉感饱满中年熟妇日本| 日韩欧美亚洲中文乱码| 亚洲伊人久久精品影院| 午夜天堂av天堂久久久| 精品久久亚洲中文无码| 97在线精品视频免费| 97超碰国产精品无码分类| 人澡人人澡人人澡欧美| 国产xxxx视频在线观看| 成人免费看片又大又黄| 无遮挡呻吟娇喘视频免费播放| 日日婷婷夜日日天干| 婷婷综合缴情亚洲| 特级aaaaaaaaa毛片免费视频| 日韩成人一区二区三区在线观看| 免费国产a国产片高清网站| 少妇人妻陈艳和黑人教练| 巨乳美乳一区二区三区| 久久人妻av无码中文专区| 久久国产精品免费一区二区三区| 欧美黑人又粗又硬xxxxx喷水| 欧美人与动牲交欧美精品| 日韩精品无码熟人妻视频| 曰韩内射六十七十老熟女影视| 99久久精品美女高潮喷水| 国产成人无码免费视频麻豆| 天天躁夜夜躁狠狠综合2020| 欧洲成人午夜精品无码区久久| 国产精品久久久久9999赢消| 亚洲精品无码久久千人斩| 中文国产成人精品久久久| 玩两个丰满老熟女久久网| 国产乱色精品成人免费视频| 人妻无码一区二区三区av| 97超碰国产精品无码分类| 亚洲国产婷婷综合在线精品|