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  4. Recombinant Pig Thioredoxin-interacting protein (TXNIP)

Recombinant Pig Thioredoxin-interacting protein (TXNIP)

  • 中文名稱：
    野豬TXNIP重組蛋白
  • 貨號：
    CSB-YP639475PI
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    野豬TXNIP重組蛋白
  • 貨號：
    CSB-EP639475PI
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    野豬TXNIP重組蛋白
  • 貨號：
    CSB-EP639475PI-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    野豬TXNIP重組蛋白
  • 貨號：
    CSB-BP639475PI
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    野豬TXNIP重組蛋白
  • 貨號：
    CSB-MP639475PI
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    TXNIP; Thioredoxin-interacting protein
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-391
  • 氨基酸序列
    MVMFKKIKSF EVVFNDPEKV YGCGEKVAGR VIVEVCEVTR IKAVRILACG VAKVLWMQGS QQCKQTLDYL RYEDTLLLDD HPTGENEMVI MRPGNKYEYK FGFELPQGPL GTSFKGKYGC VDYWVKAFLD RPSQPTQETK KHFEVMDLVD VNTPDLMAPV SAKKEKKVSC MFIPDGRVSV SARIDRKGFC EGDEINIHAD FENTCSRIVV PKAAIVARHT YLANGQTKVL TQKLSSVRGN HIISGTCASW RGKSLRVQKI RPSILGCNIL RVEYFLLIYV SVPGSKKVIL DLPLVIGSRS GLSSRTSSMA SRTSSEMSWV DLNIPDTPEA PPCYMDIIPE DHRLESPTTP LLDDTDGSQD SPIFMYAPEF KFMPPPTYSE VDPCILNNNV Q
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.
  • 基因功能參考文獻：
    1. The molecular characterization of porcine TXNIP gene, is described. PMID: 23053948
    2. single-marker and haplotype analyses revealed significant effects of TXNIP on hot carcass weight, test daily gain, and lifetime daily gain PMID: 17406940
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Arrestin family
  • 數據庫鏈接：


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