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  4. Recombinant Pig Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial (OXCT1)

Recombinant Pig Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial (OXCT1)

  • 中文名稱：
    野豬OXCT1重組蛋白
  • 貨號：
    CSB-YP641840PI
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    野豬OXCT1重組蛋白
  • 貨號：
    CSB-EP641840PI
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    野豬OXCT1重組蛋白
  • 貨號：
    CSB-EP641840PI-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    野豬OXCT1重組蛋白
  • 貨號：
    CSB-BP641840PI
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    野豬OXCT1重組蛋白
  • 貨號：
    CSB-MP641840PI
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    OXCT1; OXCT; SCOT; Succinyl-CoA:3-ketoacid coenzyme A transferase 1; mitochondrial; EC 2.8.3.5; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    40-520
  • 氨基酸序列
    T KFYTDAVEAV KDIPNGATVL VGGFGLCGIP ENLIGALLKT GVKELTAVSN NAGVDNFGLG LLLQSKQIKR MISSYVGENA EFERQYLAGE LEVELTPQGT LAERIRAGGA GVPAFYTSTG YGTLVQEGGS PIKYNKDGSI AIASKPREVR EFNGQHFILE EAIRGDFALV KAWKADQAGN VTFRKSARNF NLPMCKAAET TVVEVEEIVD IGSFAPEDIH IPKIYVHRLV KGEKYEKRIE RLSVRKEEDV KTRSGKLGDN VRERIIKRAA LEFEDGMYAN LGIGIPLLAS NFISPNMTVH LQSENGILGL GPYPLQNEVD ADLINAGKET VTVLPGASYF SSDESFAMIR GGHVNLTMLG AMQVSKYGDL ANWMIPGKLV KGMGGAMDLV SSAKTKVVVT MEHSAKGNAH KIMEKCTLPL TGKQCVNRII TEKAVFDVDS KKGLTLIELW EGLTVDDIKK STGCDFAVSP KLIPMQQVTT
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  • 基因功能參考文獻：
    1. mechanism of SCOT catalysis PMID: 20977214
    2. Structure of the CoA transferase from pig heart to 1.7 A resolution PMID: 15388917
    3. On the basis of these results the conformational change in SCOT was deduced to be a domain rotation of 17 degrees coupled with movement of two loops: res. 321-329 that interact with succinate or acetoacetate and res. 374-386 that interact with CoA. PMID: 17718512
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    3-oxoacid CoA-transferase family
  • 數據庫鏈接：


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