在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Pig Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1), partial

  • 中文名稱:
    Recombinant Pig Steroid 17-alpha-hydroxylase/17,20 lyase(CYP17A1) ,partial
  • 貨號:
    CSB-YP006392PI
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Pig Steroid 17-alpha-hydroxylase/17,20 lyase(CYP17A1) ,partial
  • 貨號:
    CSB-EP006392PI
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Pig Steroid 17-alpha-hydroxylase/17,20 lyase(CYP17A1) ,partial
  • 貨號:
    CSB-EP006392PI-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Pig Steroid 17-alpha-hydroxylase/17,20 lyase(CYP17A1) ,partial
  • 貨號:
    CSB-BP006392PI
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Pig Steroid 17-alpha-hydroxylase/17,20 lyase(CYP17A1) ,partial
  • 貨號:
    CSB-MP006392PI
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    CYP17A1; CYP17; Steroid 17-alpha-hydroxylase/17,20 lyase; EC 1.14.14.19; 17-alpha-hydroxyprogesterone aldolase; EC 1.14.14.32; CYPXVII; Cytochrome P450 17A1; Cytochrome P450-C17; Cytochrome P450c17; Steroid 17-alpha-monooxygenase
  • 種屬:
    Sus scrofa (Pig)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione. Has 16-alpha hydroxylase activity. Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA. Also 16-alpha hydroxylates androgens, relevant for estriol synthesis. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
  • 基因功能參考文獻:
    1. The immunolocalization of P450c17, detected in the ovaries of pregnant pigs and fetal porcine gonads, indicates the potential sites of androgen synthesis. PMID: 21804630
    2. LH and insulin stimulate transcription of -976/+31 bp 5'-upstream cis-acting region of porcine CYP17 gene. Maximal transcriptional responsiveness requires proximal Sp1 and AP-2-like sequences -193 to -180 bp 5' upstream of transcriptional start site. PMID: 15001547
    3. Synthesis of androstenone in pig testis is not directly affected by any polymorphisms in the coding region of the porcine CYP17 gene. PMID: 16341769
    4. effect of substrate on the redox potential for each P450c17 was measured in the presence of pregnenolone, progesterone, 17alpha-hydroxypregnenolone and 17alpha-hydroxyprogesterone PMID: 16595705
    5. These results demonstrate the differential effects of two forms of CYB5 on the three activities of porcine CYP17A1 and show that CYB5B does not stimulate the andien-beta synthase activity of CYP17A1. PMID: 19101629

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane. Microsome membrane.
  • 蛋白家族:
    Cytochrome P450 family
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲精品av中文字幕在线 | 西西艺术人像摄影| 欧美大波少妇在厨房被| 日本一卡2卡3卡4卡无卡免费网站 丰满少妇人妻无码专区 | 国产亚洲精品一区在线播放| 国产性色播播毛片| 一品二品三品中文字幕| 国产在线观看无码的免费网站| 一区二区久久久久草草| 免费无码成人av片在线在线播放 | 精品爆乳一区二区三区无码av| 亚洲性视频免费视频网站| 成人看片黄a免费看| 国产精品一区二区久久不卡| 人人做人人爽人人爱| 真人做人60分钟啪啪免费看| 国产成人精品高清在线观看93| 日本在线视频www鲁啊鲁| 极品熟妇大蝴蝶20p| 亚洲欧美日韩中文加勒比| 无码av喷白浆在线播放| 国产欧美在线观看不卡| 美女张开腿黄网站免费下载| 制服丝袜有码中文字幕在线 | 国产专区一线二线三线码 | 国产精品人人做人人爽人人添| www国产精品内射老师| 亚洲一二三四2021不卡| 色欲av蜜桃一区二区三| 日韩免费视频| 人妻熟人中文字幕一区二区| 香蕉啪视频在线观看视频久| 国产在线永久视频| 欧美日韩国产精品自在自线| 亚洲高清专区日韩精品| 大胆日本熟妇xxxx| 精品人伦一区二区三区蜜桃免费| 国产成人久久a免费观看| 亚洲国产精品成人影片久久| 欧美人与动另类xxxx| 亚洲日韩av一区二区三区中文|