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  4. Recombinant Pig Sperm flagellar protein 2 (SPEF2), partial

Recombinant Pig Sperm flagellar protein 2 (SPEF2), partial

  • 中文名稱：
    野豬SPEF2重組蛋白
  • 貨號：
    CSB-YP643180PI
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    野豬SPEF2重組蛋白
  • 貨號：
    CSB-EP643180PI
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    野豬SPEF2重組蛋白
  • 貨號：
    CSB-EP643180PI-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    野豬SPEF2重組蛋白
  • 貨號：
    CSB-BP643180PI
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    野豬SPEF2重組蛋白
  • 貨號：
    CSB-MP643180PI
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SPEF2
  • Uniprot No.：
  • 別名：
    SPEF2; KPL2; Sperm flagellar protein 2; Protein KPL2
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Required for correct axoneme development in spermatozoa. Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein-mediated protein transport during spermatogenesis. Also plays a role in bone growth where it seems to be required for normal osteoblast differentiation.
  • 基因功能參考文獻：
    1. PRLR was identified as down-regulated in the oviduct of immotile short tail sperm (ISTS) homozygous sows. The methylation pattern of the PRLR gene region appeared unaffected. PMID: 24712415
    2. KPL2 gene is important for correct axoneme development and provide insight into abnormal sperm development and infertility disorders PMID: 16549801
    3. Integration of a transposition-competent L1 element into KPL2 is responsible for the defective spermatozoa and infertility. PMID: 17610085
  • 相關疾病：
    Defects in SPEF2 are a cause of immotile short-tail sperm defects, an autosomal recessive disease only found in the Finnish Yorkshire pig population. It specifically affects the axoneme structure of sperm flagella, whereas cilia in other tissues appear unaffected.
  • 亞細胞定位：
    Cell projection, cilium, flagellum. Cytoplasm. Golgi apparatus.
  • 組織特異性：
    Predominantly expressed in ciliated tissues. Mainly expressed in testis, followed by trachea. Also expressed at lower level in lung, kidney and liver.
  • 數據庫鏈接：


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