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  4. Recombinant Pig Natural resistance-associated macrophage protein 1 (SLC11A1), partial

Recombinant Pig Natural resistance-associated macrophage protein 1 (SLC11A1), partial

  • 中文名稱：
    野豬SLC11A1重組蛋白
  • 貨號：
    CSB-YP021380PI
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    野豬SLC11A1重組蛋白
  • 貨號：
    CSB-EP021380PI
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    野豬SLC11A1重組蛋白
  • 貨號：
    CSB-EP021380PI-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    野豬SLC11A1重組蛋白
  • 貨號：
    CSB-BP021380PI
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    野豬SLC11A1重組蛋白
  • 貨號：
    CSB-MP021380PI
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC11A1
  • Uniprot No.：
  • 別名：
    SLC11A1; NRAMP1; Natural resistance-associated macrophage protein 1; NRAMP 1; Solute carrier family 11 member 1
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.
  • 基因功能參考文獻：
    1. Study shows that, before and after weaning, Nramp1 was highly expressed in digestive (stomach) and intestinal (duodenum, jejunum, and ileum) tissues, further indicating a genetic role in both immune regulation to compensate for weaning stress and enhanced development of intestinal immunity. PMID: 28362979
    2. The frequency of allele B and A was 0.93 and 0.90 on a total of 180 and 205 pigs for the polymorphism in intron 1 and intron 2 of the Nramp1 gene respectively in a mixed population of hybrid and purebred pigs. PMID: 24757812
    3. Genomic organization and polymorphisms detected by denaturing HPLC of porcine NRAMP1 gene are reported. PMID: 17654007
    4. a significant correlation between different genotypes of Nramp1 gene and immune function and production performance PMID: 18407056
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    NRAMP family
  • 數據庫鏈接：


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