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  4. Recombinant Pig Estrogen receptor beta (ESR2), partial

Recombinant Pig Estrogen receptor beta (ESR2), partial

  • 中文名稱：
    野豬ESR2重組蛋白
  • 貨號：
    CSB-YP893169PI
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    野豬ESR2重組蛋白
  • 貨號：
    CSB-EP893169PI
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    野豬ESR2重組蛋白
  • 貨號：
    CSB-EP893169PI-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    野豬ESR2重組蛋白
  • 貨號：
    CSB-BP893169PI
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    野豬ESR2重組蛋白
  • 貨號：
    CSB-MP893169PI
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    ESR2; NR3A2Estrogen receptor beta; ER-beta; Nuclear receptor subfamily 3 group A member 2
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
  • 基因功能參考文獻：
    1. There were no statistical differences between the BB genotype and the AB genotype of ESR2 locus in regard to the examined traits. However, a noticeable superiority (P < 0.01) of the BB genotype compared to the homozygous AA genotype, adding almost 2 piglets/litter in TNB and NBA trait, was found. PMID: 27824510
    2. steroid hormones, AhR and estrogen receptor beta are affected by TCDD and genistein in granulosa cells of medium porcine follicles PMID: 26568065
    3. Results suggest that expression levels of protease activated receptors 1 and 2 (PAR-1 and PAR-2) associate with breast cancer outcome in an estrogen receptor (ER)-dependent manner. PMID: 26244666
    4. results might shed new light on the roles of estrogen receptor 2(ESR2) in spermatogenesis as candidate for boar fertility PMID: 22212297
    5. study is the first one to demonstrate the presence of estrogen receptors alpha and beta in the porcine uterus not only at the beginning but also at mid- and late pregnancy PMID: 19645857
    6. Downregulation of the ERs, particularly ERalpha in the myometrium and endometrial stroma, might be a relevant mechanism in the antagonism of estrogenic effects by dihydrotestosterone in the pig uterus. PMID: 14522825
    7. the results of the present study suggest the involvement of estrogen receptor beta in estrogen modulation of pig epididymal function PMID: 15046395
    8. findings suggest that testicular oestrogen receptors alpha and beta may be important factors contributing to onset and maintenance of spermatogenesis in the boar PMID: 15943697
    9. ERbeta mRNA was found only in Sertoli cells in the testis. PMID: 16249893
    10. positive staining for ERalpha in the nuclei of skeletal muscle cells, while the ERbeta stain showed positive signals in nuclei and cytoplasm of skeletal myofibers and myoblasts derived from satellite cells PMID: 16897031
    11. ESR2 gene polymorphisms are associated with litter size. PMID: 16965408
    12. The objective of this study was to search for polymorphisms in the coding region of the estrogen receptors 1 and 2 (ESR1 and ESR2) and to analyze the effects of these variants and the well known intronic ESR1 PvuII polymorphism on litter size. PMID: 17306201
    13. These data demonstrate novel and differential mechanisms by which ERalpha and ERbeta activation control coronary artery vasoreactivity in males and females and regulate vascular NO and O(2)(-) formation. PMID: 17470727
    14. Pig ejaculated spermatozoa express estrogen receptor. PMID: 17553131
    15. The expression of mRNAs for ERalpha, ERbeta and PR in the sow uterus differed between endometrium and myometrium as well as with stages of the estrous cycle and early pregnancy. PMID: 18547755

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Nuclear hormone receptor family, NR3 subfamily
  • 數據庫鏈接：


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