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  4. Recombinant Pig Cytochrome P450 19 type I (CYP19A1), partial

Recombinant Pig Cytochrome P450 19 type I (CYP19A1), partial

  • 中文名稱：
    Recombinant Pig Cytochrome P450 19 type I(CYP19A1) ,partial
  • 貨號：
    CSB-YP643691PI
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Pig Cytochrome P450 19 type I(CYP19A1) ,partial
  • 貨號：
    CSB-EP643691PI
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Pig Cytochrome P450 19 type I(CYP19A1) ,partial
  • 貨號：
    CSB-EP643691PI-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Pig Cytochrome P450 19 type I(CYP19A1) ,partial
  • 貨號：
    CSB-BP643691PI
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Pig Cytochrome P450 19 type I(CYP19A1) ,partial
  • 貨號：
    CSB-MP643691PI
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CYP19A1
  • Uniprot No.：
  • 別名：
    CYP19A1; CYP19Aromatase 1; EC 1.14.14.14; CYPXIXA1; Cytochrome P-450AROM; Cytochrome P450 19 type I; Estrogen synthase
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
  • 基因功能參考文獻：
    1. liver receptor homolog (LRH)-1, not CYP19A1, is a direct functional target of miR-1275. PMID: 29378329
    2. CYP19A1 is involved in sperm fertility and its expression in sperm plays an important role in fertilization. PMID: 25621494
    3. P450arom was expressed in all layers of the arterial and venous vessels of the spermatic cord with higher intensity of staining in June long daylight) compared to December(short daylight). PMID: 25454494
    4. Decreased estradiol production via suppression of aromatase may be one of the mechanisms by which miR-378 regulates the maturation of cumulus-oocyte complexes. PMID: 25628423
    5. This study tested whether prenatal and neonatal exposure to antiandrogen flutamide affected ovarian 17beta-estradiol synthesis and the associated gene expression in large antral follicles of adult pigs. PMID: 23043943
    6. show that micro-RNA378 (miR-378) is spatiotemporally expressed in porcine granulosa cells, the cells that generate estradiol in the ovary during follicular development, in an inverse manner compared with the expression of aromatase PMID: 21846797
    7. Pig ejaculated spermatozoa express aromatase. PMID: 17553131
    8. The presence of aromatase and 11beta-HSD 2 in Leydig cells increased, together with germ and Sertoli cell numbers. PMID: 18462613
    9. This study demonstrates that transferrin had a dose-dependent inhibitory effect on follicle stimulating hormone-stimulated aromatase activity. PMID: 19141392

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  • 亞細胞定位：
    Membrane; Peripheral membrane protein.
  • 蛋白家族：
    Cytochrome P450 family
  • 數據庫鏈接：

    KEGG: ssc:403331

    UniGene: Ssc.56422



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