在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Phoca vitulina Interleukin-6 (IL6)

  • 中文名稱:
    Recombinant Phoca vitulina Interleukin-6(IL6)
  • 貨號(hào):
    CSB-YP631730EUR
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Phoca vitulina Interleukin-6(IL6)
  • 貨號(hào):
    CSB-EP631730EUR
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Phoca vitulina Interleukin-6(IL6)
  • 貨號(hào):
    CSB-EP631730EUR-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Phoca vitulina Interleukin-6(IL6)
  • 貨號(hào):
    CSB-BP631730EUR
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Phoca vitulina Interleukin-6(IL6)
  • 貨號(hào):
    CSB-MP631730EUR
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    IL6; Interleukin-6; IL-6; Fragment
  • 種屬:
    Phoca vitulina (Harbor seal)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    27-209
  • 氨基酸序列
    GPVG GESQADATSN RPPLTSPDKM EEFIKYILGK ISALRKEMCD KYNKCEDSKE ALAENNLRLP KLAEKDGCFQ SGFNQETCLT RITTGLLEFQ IHLKYIQANY EGNKEDANSV YISTKLLVQM LMKKVKSQDE VTTPDPTTDT SLQAILKAQD KWLKHTTIHL ILRSLEDFLQ FSLRAVRIM
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.; IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury. In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells.; Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability. Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF. Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance. 'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis. Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand. Also acts as a myokine. Plays a protective role during liver injury, being required for maintenance of tissue regeneration. Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection. Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration.
  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    IL-6 superfamily


主站蜘蛛池模板: 日韩无套无码精品| 亚洲性色av性色在线观看 | 亚洲天天做日日做天天欢毛片| 粉色午夜视频| 无码专区无码专区视频网址| 日日碰狠狠丁香久燥| 男女啪啪永久免费观看网站| 日产亚洲一区二区三区| 亚洲婷婷开心色四房播播| 99热这里只有精品国产免费免费| 丰满少妇在线观看网站| 亚洲日韩乱码一区二区三区四区| 娇妻被黑人粗大高潮白浆| 国产在线看片免费视频 | 午夜成人无码福利免费视频| 亚洲成a人片77777kkkk| 国产 高潮 抽搐 正在播放| 亚洲国产成人在人网站天堂| 国产一区日韩二区欧美三区| 小雪尝禁果又粗又大的视频| 国产日产欧产精品精品免费| 无码丰满熟妇bbbbxxx| 国产精品欧美亚洲韩国日本久久| 成在人av抽搐高潮喷水流白浆| 国产在线码观看清码视频| 国产精品白丝av网站在线观看| 国产av寂寞骚妇| 无码欧美黑人xxx一区二区三区| 2021国产精品香蕉在线观看| 内射白嫩少妇超碰| 国精产品一品二品国精品69xx| 亚洲性av免费| 国产亚洲视频在线观看网址| 国产精品人人做人人爽| 老子午夜精品无码| 成人无码在线视频网站| 亚洲精品成人av在线| 亚洲国产精品成人无码区| 最新国产精品拍自在线观看| 午夜精品影视国产一区在线麻豆| 丰满少妇被猛烈进入无码|