在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Partitioning defective protein 6 (par-6)

Recombinant Partitioning defective protein 6 (par-6)

  • 中文名稱：
    秀麗隱桿線蟲par-6重組蛋白
  • 貨號：
    CSB-YP885652CXY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲par-6重組蛋白
  • 貨號：
    CSB-EP885652CXY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲par-6重組蛋白
  • 貨號：
    CSB-EP885652CXY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲par-6重組蛋白
  • 貨號：
    CSB-BP885652CXY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲par-6重組蛋白
  • 貨號：
    CSB-MP885652CXY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    par-6
  • Uniprot No.：
  • 別名：
    par-6; T26E3.3Partitioning defective protein 6
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-309
  • 氨基酸序列
    MSYNGSYHQN HHSTLQVKSK FDSEWRRFSI PMHSASGVSY DGFRSLVEKL HHLESVQFTL CYNSTGGDLL PITNDDNLRK SFESARPLLR LLIQRRGESW EEKYGYGTDS DKRWKGISSL MAQKPPKRSY SISNPEDFRQ VSAIIDVDIV PEAHRRVRLC KHGQERPLGF YIRDGTSVRV TERGVVKVSG IFISRLVDGG LAESTGLLGV NDEVLEVNGI EVLGKTLDQV TDMMVANAHN LIITVKPANQ RNTLSRGPSQ QGTPNASEMS AATAAATGGI QRPMKMNGSS DGSYHPKQHD ANDSDSGED
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Necessary for apicobasal and anterior-posterior asymmetries associated with cell adhesion and gastrulation during the first few cell cycles of embryogenesis. Required for localizing/ maintaining par-3 at the cell periphery. Regulates mes-1 expression and/or localization pattern during early embryogenesis. Acts together with par-3 and pkc-3 in maintaining epithelial cell polarity in the distal spermatheca. Plays a role in endosome and Golgi body positioning.
  • 基因功能參考文獻：
    1. we find that vab-1 lies in the same genetic pathway as cdc-42 and is responsible for polarizing CDC-42 activity to the medial tip. Together, these data establish a previously uncharacterized role for polarized CDC-42, in conjunction with PAR-6, PAR-3 and an Eph receptor(vab-1), during epithelial intercalation. PMID: 27861585
    2. the arcade cell epithelium polarizes by a PAR-6-mediated pathway that is independent of E-cadherin, beta-integrin and beta-laminin. PMID: 25773364
    3. PAR-3 and PAR-6 function in cytokinesis may be partially redundant and play a role in the maintenance of DYN-1 in the cleavage furrow. PMID: 22887994
    4. evidence PAR polarity arises from coupling of advective transport by flowing cell cortex to a multistable PAR reaction-diffusion system; advection in active, flowing medium provides mechanism for mechanically templated pattern formation in development PMID: 22021673
    5. Centrosomes localize apically by first moving toward lateral foci of the conserved polarity proteins PAR-3 and PAR-6, then move together with these foci toward the future apical surface. Embryos lacking PAR-3 fail to localize their centrosomes apically. PMID: 22425160
    6. PAR-2 and PAR-6, which localize to opposing PAR domains, undergo exchange between well mixed cytoplasmic populations and laterally diffusing membrane-associated states PMID: 21518794
    7. Binding to PKC-3, but not to PAR-3 or to a conventional PDZ domain ligand, is required for PAR-6 function in C. elegans PMID: 20122916
    8. PAR proteins function in both apicobasal and anterior-posterior asymmetry during the first few cell cycles of embryogenesis. PMID: 13129846
    9. CDC-37-mediated inhibition of the CDC-42-dependent binding site and PAR-3-mediated release of this inhibition provide a key mechanism for the anterior accumulation of PAR-6. PMID: 16943281
    10. CDC-42 interaction with PAR-6 is not required for the initial establishment of asymmetry but is required for maximal cortical accumulation of PAR-6 and to maintain its asymmetry. PMID: 16996049
    11. PAR-6 is required for junction formation but not apicobasal polarization in C. elegans embryonic epithelial cells. PMID: 17314130
    12. nos-3 loss of function mutant suppresses the lethality of par-2 mutants by regulating PAR-6 protein levels. PMID: 18502413
    13. study identified a RhoGAP, PAC-1, which mediates embryo radial polarity & gastrulation by excluding PAR-6 from contacted cell surfaces; PAC-1 provides a dynamic molecular link between cell contacts & PAR proteins that polarizes embryos radially PMID: 18583611

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein. Cell junction, tight junction.
  • 蛋白家族：
    PAR6 family
  • 組織特異性：
    Colocalized with par-3 at all stages in early embryos, at the anterior cortex of the embryo. Patchy expression observed at the periphery after completion of meiosis I and in meiosis II, which on completion of metaphase II, is restricted to the anterior 85
  • 數據庫鏈接：

    KEGG: cel:CELE_T26E3.3

    STRING: 6239.T26E3.3a.3

    UniGene: Cel.8562



主站蜘蛛池模板： 国产99久9在线视频 | 传媒| 亚洲熟妇av日韩熟妇在线| 日本牲交大片免费观看| 久久久久久人妻毛片a片 | 久久精品成人免费国产| 国产亚洲精品国产福利你懂的| 国产色a在线观看| 99久久精品国产一区二区蜜芽 | 80s国产成年女人毛片| 国产精品沙发系列| 国产成人片无码免费视频软件| 国产女女做受ⅹxx高潮| 亚洲三区在线观看无套内射| 亚洲成av人在线视猫咪| 丰满又黄又爽少妇毛片| 1000部夫妻午夜免费| 国产午夜福利精品一区二区三区 | 无码动漫性爽xo视频在线观看| 亚洲欲色欲香天天综合网| 日韩一欧美内射在线观看 | 免费国产午夜视频在线| 人妻丰满av无码久久不卡| 中文在线а√在线天堂中文| 亚洲精品一区二区中文字幕| 欧美xxxxx精品| 国产内射合集颜射| 中文字幕av无码不卡免费| 免免费国产aaaaa片| 国产精品自在欧美一区| 日本又黄又潮娇喘视频| 国产又色又刺激高潮视频| 精品香蕉一区二区三区 | 久久亚洲精品成人av二次元| 日韩人妻无码一区二区三区俄罗斯| 亚洲色婷婷久久精品av蜜桃久久| 亚洲精品国产成人精品| 亚洲国产精品自在拍在线播放蜜臀 | 亚洲成a人片在线播放| 国产成人久久av免费| 亚洲精品97久久中文字幕无码| 国产成人乱色伦区|