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  4. Recombinant Neisseria meningitidis serogroup B Protein hfq (hfq)

Recombinant Neisseria meningitidis serogroup B Protein hfq (hfq)

  • 中文名稱：
    腦膜炎奈瑟菌血清組hfq重組蛋白
  • 貨號：
    CSB-YP350716NGG
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    腦膜炎奈瑟菌血清組hfq重組蛋白
  • 貨號：
    CSB-EP350716NGG
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    腦膜炎奈瑟菌血清組hfq重組蛋白
  • 貨號：
    CSB-EP350716NGG-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    腦膜炎奈瑟菌血清組hfq重組蛋白
  • 貨號：
    CSB-BP350716NGG
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    腦膜炎奈瑟菌血清組hfq重組蛋白
  • 貨號：
    CSB-MP350716NGG
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    hfq
  • Uniprot No.：
  • 別名：
    hfq; NMB0748; RNA-binding protein Hfq
  • 種屬：
    Neisseria meningitidis serogroup B (strain MC58)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-97
  • 氨基酸序列
    MTAKGQMLQD PFLNALRKEH VPVSIYLVNG IKLQGQVESF DQYVVLLRNT SVTQMVYKHA ISTIVPARSV NLQHENRPQA APTSTLVQVE TVQQPAE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.
  • 基因功能參考文獻：
    1. The authors show that Hfq binds the AniS transcript in vitro and is necessary for the downregulation of the identified target mRNAs in vivo. PMID: 21338417
    2. Hfq is dispensable for NrrF-mediated regulation of the succinate dehydrogenase genes, regulates sodB in an iron-responsive mechanism, and influences the expression of several ORFs as well as intergenic regions via iron-independent mechanisms. PMID: 20430815
    3. Importantly, in ex vivo and in vivo models of infection the Hfq mutant is attenuated. PMID: 19223479
    4. Involved in the regulation of a variety of components contributing to the survival and establishment of meningococcal disease. Involved in the regulation of expression of components involved in general metabolic pathways, iron metabolism, and virulence. PMID: 19374669
  • 蛋白家族：
    Hfq family
  • 數據庫鏈接：

    KEGG: nme:NMB0748

    STRING: 122586.NMB0748



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