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Recombinant Neisseria meningitidis serogroup B Ferric uptake regulation protein (fur)

  • 中文名稱:
    腦膜炎奈瑟菌血清組fur重組蛋白
  • 貨號:
    CSB-YP362982NGG
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    腦膜炎奈瑟菌血清組fur重組蛋白
  • 貨號:
    CSB-EP362982NGG
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    腦膜炎奈瑟菌血清組fur重組蛋白
  • 貨號:
    CSB-EP362982NGG-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    腦膜炎奈瑟菌血清組fur重組蛋白
  • 貨號:
    CSB-BP362982NGG
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    腦膜炎奈瑟菌血清組fur重組蛋白
  • 貨號:
    CSB-MP362982NGG
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    fur
  • Uniprot No.:
  • 別名:
    fur; NMB0205Ferric uptake regulation protein; Ferric uptake regulator
  • 種屬:
    Neisseria meningitidis serogroup B (strain MC58)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-144
  • 氨基酸序列
    MEKFNNIAQL KDSGLKVTGP RLKILDLFET HAEEHLSAED VYRILLEEGV EIGVATIYRV LTQFEQAGIL QRHHFETGKA VYELDKGDHH DHIVCVKCGE VTEFHNPEIE ALQDKIAEEN GYRIVDHALY MYGVCSDCQA KGKR
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of the fbp protein.
  • 基因功能參考文獻:
    1. This study indicates that the expression of NMB0419 is associated with transcriptional changes counterbalancing the regulatory function of Fur, offering a new perspective on regulatory mechanisms involved in meningococcal interaction with epithelial cells, and suggests new insights into the roles of Sel1-like repeat-containing genes in other bacteria. PMID: 28264906
    2. Data characterize the role of iron and Fur in the regulation of the NMB1436-38 operon and we have mapped the promoter and the Fur binding site. PMID: 15522080
    3. By using the Fur-null mutant and its complemented derivative, we identified 83 genes whose transcription is controlled by Fur PMID: 16547035
    4. one small RNA, herein named NrrF (for neisserial regulatory RNA responsive to iron [Fe]) was demonstrated to be both iron responsive and Fur regulated PMID: 17351036
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Fur family
  • 數據庫鏈接:

    KEGG: nme:NMB0205

    STRING: 122586.NMB0205



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