在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Voltage-dependent L-type calcium channel subunit beta-1 (Cacnb1)

Recombinant Mouse Voltage-dependent L-type calcium channel subunit beta-1 (Cacnb1)

  • 中文名稱：
    Recombinant Mouse Voltage-dependent L-type calcium channel subunit beta-1(Cacnb1)
  • 貨號：
    CSB-YP854513MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Voltage-dependent L-type calcium channel subunit beta-1(Cacnb1)
  • 貨號：
    CSB-EP854513MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Voltage-dependent L-type calcium channel subunit beta-1(Cacnb1)
  • 貨號：
    CSB-EP854513MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Voltage-dependent L-type calcium channel subunit beta-1(Cacnb1)
  • 貨號：
    CSB-BP854513MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Voltage-dependent L-type calcium channel subunit beta-1(Cacnb1)
  • 貨號：
    CSB-MP854513MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Cacnb1; Cacnlb1Voltage-dependent L-type calcium channel subunit beta-1; CAB1; Calcium channel voltage-dependent subunit beta 1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-597
  • 氨基酸序列
    MVQKSGMSRG PYPPSQEIPM EVFDPSPQGK YSKRKGRFKR SDGSTSSDTT SNSFVRQGSA ESYTSRPSDS DVSLEEDREA LRKEAERQAL AQLEKAKTKP VAFAVRTNVG YNPSPGDEVP VQGVAITFEP KDFLHIKEKY NNDWWIGRLV KEGCEVGFIP SPVKLDSLRL LQEQTLRQNR LSSSKSGDNS SSSLGDVVTG TRRPTPPASA KQKQKSTEHV PPYDVVPSMR PIILVGPSLK GYEVTDMMQK ALFDFLKHRF DGRISITRVT ADISLAKRSV LNNPSKHIII ERSNTRSSLA EVQSEIERIF ELARTLQLVA LDADTINHPA QLSKTSLAPI IVYIKITSPK VLQRLIKSRG KSQSKHLNVQ IAASEKLAQC PPEMFDIILD ENQLEDACEH LAEYLEAYWK ATHPPSSTPP NPLLNRTMAT AALAASPAPV SNLQGPYLAS GDQPLDRATG EHASVHEYPG ELGQPPGLYP SNHPLGRAGT LRALSRQDTF DADTPGSRNS AYTEPGDSCV DMETDPSEGP GPGDPAGGGT PPARQGSWED EEDYEEEMTD NRNRGRNKAR YCAEGGGPVL GRNKNELEGW GQGVYTR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit.
  • 基因功能參考文獻：
    1. Structural and biophysical analyses of the skeletal dihydropyridine receptor beta subunit beta1a reveal critical roles of domain interactions for stability. PMID: 28351836
    2. The present study reveals that the C-terminal of the beta1a subunit changes conformation in the presence of RyR1 consistent with an interaction between the C-terminal of beta1a and RyR1 in resting myotubes. PMID: 26114725
    3. TnT3 facilitates Cavbeta1a nuclear recruitment, suggesting that the two proteins play a heretofore unknown role during early muscle differentiation in addition to their classical role in excitation-contraction coupling regulation. PMID: 25981458
    4. The motif Leu(496)-Leu(500)-Trp(503) within the bet1a C-terminal tail plays a nonessential role in the bidirectional DHPR/RyR1 signaling that supports skeletal-type excitation-contraction coupling. PMID: 25384984
    5. Cavbeta1a acts as a Cav-independent regulator of gene expression in MPCs, and is required for their normal expansion during myogenic development. PMID: 24934157
    6. Data suggest that specific hydrophobic surface residues in calcium channel voltage-dependent beta1a subunit C-terminus bind to RyR1 and increase channel activity in lipid bilayers and thus may support skeletal muscle excitation-contraction coupling. PMID: 22962299
    7. Cavbeta1 is predominantly expressed in the strata oriens and radiatum of the hippocampus, and only weakly in the cerebellum, in the developing mouse brain. PMID: 22737983
    8. The results of this study indicated that the skeletal muscle DHPR retrogradely regulates the patterning and formation of the Neuromuscular junction. PMID: 21441923
    9. Mice with cardiac-specific sequestration of the beta-subunit of the L-type calcium channel PMID: 12054671
    10. calcium channel beta1a subunits are organized in triad junctions in skeletal muscle PMID: 16317008
    11. excitation-contraction coupling in skeletal muscle involves the interplay of at least two subunits of the DHPR, namely alpha1S and beta1a, interacting with possibly different domains of RyR1 [DHPR beta1a] PMID: 16357209

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein.
  • 蛋白家族：
    Calcium channel beta subunit family
  • 組織特異性：
    Detected in the inner nuclear layer in the retina (at protein level). Detected in skeletal muscle, brain, heart and spleen.
  • 數據庫鏈接：


主站蜘蛛池模板： 少妇精品无码一区二区三区| 亚洲另类自拍丝袜第五页| 一本久道久久综合狠狠躁av| 狼人亚洲国内精品自在线| 国产成 人 综合 亚洲网站| 在线观看片免费人成视频无码| 欧美真人做爰在线观看| 国产成人一区二区三区在线| 2018国产精华国产精品| 亚洲看片lutube在线观看| 亚洲最大激情中文字幕| 午夜影视免费x看| 亚洲丰满熟女一区二区v| 亚洲国产一区二区三区| 免费裸体黄网站18禁免费| 久久精品人成免费| 日韩在线成年视频人网站观看 | 亚洲中文字幕无码不卡电影| 97久久香蕉国产线看观看| 欧美兽交xxxx×视频| 无码日日模日日碰夜夜爽| 中国女人内谢69xxxx免费视频| 午夜福利理论片在线观看| 亚洲中文字幕久久无码精品| 制服 丝袜 亚洲 中文 综合| 老男人久久青草av高清| 日本三级香港三级三级人!妇久 | 又粗又黄又硬又爽的免费视频| 久久亚洲精品情侣| 最近中文字幕mv在线视频看| 成av人片一区二区三区久久| 欧美国产国产综合视频| 亚洲精品1卡2卡三卡4卡乱码| 中文字幕无码精品亚洲资源网 | 国产成人亚洲综合网站小说| 粗大的内捧猛烈进出视频| 亚洲精品成人无码中文毛片不卡| 亚洲精品国产成人一区二区| a∨在线视频播放| 韩国v欧美v亚洲v日本v| 亚洲乱亚洲乱少妇无码99p|