在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Tudor domain-containing protein 1 (Tdrd1), partial

Recombinant Mouse Tudor domain-containing protein 1 (Tdrd1), partial

  • 中文名稱：
    小鼠Tdrd1重組蛋白
  • 貨號：
    CSB-YP858158MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Tdrd1重組蛋白
  • 貨號：
    CSB-EP858158MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Tdrd1重組蛋白
  • 貨號：
    CSB-EP858158MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Tdrd1重組蛋白
  • 貨號：
    CSB-BP858158MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Tdrd1重組蛋白
  • 貨號：
    CSB-MP858158MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Tdrd1
  • Uniprot No.：
  • 別名：
    Tdrd1; Tudor domain-containing protein 1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins.
  • 基因功能參考文獻：
    1. TDRD1 can accommodate different peptides from different proteins, and can therefore act as a scaffold protein for complex assembly in the piRNA pathway. PMID: 22996915
    2. Data suggest that the formation of complexes between MILI, MIWI and TDRD1/MTR-1 is critical for the integrated subcellular localizations of these proteins, and is presumably essential for spermatogenesis. PMID: 19735482
    3. isolated Mouse tudor repeat-1 (Mtr-1) which encodes a MYND domain and four copies of the tudor domain. Mtr-1 is expressed in germ-line cells and is most abundant in fetal prospermatogonia and postnatal primary spermatocytes. PMID: 14550528
    4. targeted mutation in Tudor domain containing 1/mouse tudor repeat 1 (Tdrd1/Mtr-1), a tudor-related gene in mice, leads to male sterility because of postnatal spermatogenic defects PMID: 17038506
    5. Tudor-related proteins, which contain multiple repeats of the Tudor domain, constitute an evolutionarily conserved class of nuage components in the germ-line, and their localization or accumulation to nuage is likely conferred by a Tudor domain structure PMID: 17141210
    6. Results suggest that Mili interacts with Tdrd1 in the nuage and chromatoid body, and that this interaction does not contribute to piRNA biogenesis but represents a regulatory mechanism that is critical for spermatogenesis. PMID: 19345100
    7. Tdrd1 ensures the entry of correct transcripts into the normal piRNA pool. PMID: 19465913

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    TDRD1 family
  • 組織特異性：
    Testis and ovary specific. Present in germ-line cells and is most abundant in fetal prospermatogonia and postnatal primary spermatocytes (at protein level).
  • 數據庫鏈接：


主站蜘蛛池模板： 国产99在线 | 中国| 人妻丝袜中文无码av影音先锋专区 | 精品国精品国产自在久国产应用| 国产成人vr精品a视频| 亚洲综合最新无码专区| 欧美性猛少妇xxxxx免费 | 亚洲 小说 欧美 激情 另类| 风流老熟女一区二区三区| 日本午夜精品一区二区三区电影| 春药高潮抽搐流白浆在线观看| 国产欧美亚洲日韩图片| 色噜噜av亚洲色一区二区 | 少妇激情av一区二区三区 | 成年丰满熟妇午夜免费视频| 极品粉嫩国产18尤物在线观看| 丝袜自慰一区二区三区| 激情综合五月丁香亚洲| 无码国内精品久久人妻 | 亚洲人成77777在线播放网站不卡| 国产精品久久一区二区三区| 西西人体做爰大胆gogo| 亚洲高清国产av拍精品青青草原| 精品久久久久久久国产潘金莲| 国产美女裸体无遮挡免费视频 | 天天做av天天爱天天爽| 欧美日韩中文在线字幕视频| 国产超碰人人爽人人做人人添| 中文字字幕在线中文乱码| 变态另类牲交乱| 欧美性xxxxx极品少妇直播| 少妇人妻邻居| 骚虎视频在线观看| 国产av精品一区二区三区小说| 久久国产亚洲高清观看| 乱色精品无码一区二区国产盗| 国产成人亚洲综合精品| 国内精品自线一区二区三区2021| 免费人成在线观看网站| 久久综合狠狠色综合伊人| a狠狠久久蜜臀婷色中文网| 丰满少妇在线观看网站|