在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Tuberoinfundibular peptide of 39 residues (Pth2)

Recombinant Mouse Tuberoinfundibular peptide of 39 residues (Pth2)

  • 中文名稱：
    小鼠Pth2重組蛋白
  • 貨號：
    CSB-YP856297MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Pth2重組蛋白
  • 貨號：
    CSB-EP856297MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Pth2重組蛋白
  • 貨號：
    CSB-EP856297MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Pth2重組蛋白
  • 貨號：
    CSB-BP856297MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Pth2重組蛋白
  • 貨號：
    CSB-MP856297MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Pth2
  • Uniprot No.：
  • 別名：
    Pth2; Tip39; Tipf39; Tuberoinfundibular peptide of 39 residues; TIP39; Parathyroid hormone 2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Cytoplasmic domain
  • 表達區域：
    62-100
  • 氨基酸序列
    SLALADDAA FRERARLLAA LERRRWLDSY MQKLLLLDAP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. May inhibit cell proliferation via its action of PTH2R activation. Neuropeptide which may also have a role in spermatogenesis. May activate nociceptors and nociceptive circuits.
  • 基因功能參考文獻：
    1. TIP39-PTH2R system appears to be a previously unrecognized mechanism for regulation of extracellular matrix formation and wound repair. PMID: 28454729
    2. This study demonstrated that TIP39 signaling plays a role in fear incubation and suggest that may serve to ameliorate the long-term negative outcome of traumatic experience via PTH2R-expressing neurons in the Medial Nucleus of the Amygdala. PMID: 26338326
    3. Data indicate that the nociceptive phenotype of TIP39-knockout {KO) mice was similar to the PTH2R-KO. PMID: 23878240
    4. TIP39/PTH2R signaling inhibits proliferation and alters differentiation of chondrocytes by modulating SOX9 expression PMID: 19706789
    5. Mice with PTH2R-null mutation lacking thermoregulation. PMID: 22159128
    6. Involvement of the TIP39/PTH2-R system in the pathways involved in the successful development of the pups. PMID: 21535248
    7. This study demonistrated that suggested that TIP39 modulates long-term fear recall and that mice lacking TIP39 or its receptor are tools for investigating fear-related psychopathologies. PMID: 21382418
    8. these results suggest that the TIP39/PTH2-R system modulates the effects of novelty exposure on memory performance, potentially by acting on noradrenergic signaling PMID: 20796031
    9. Data indicate that the TIP39 ligand/PTH2 receptor system provides facilitatory regulation of the hypothalamic-pituitary-adrenal axis via hypothalamic glutamatergic neurons and that it may regulate other neuroendocrine systems by a similar mechanism. PMID: 20853513
    10. TIP39 signaling modulates nociception, very likely by inhibiting endocannabinoid circuitry at a supraspinal level PMID: 20696160
    11. PTH1 receptor antagonism PMID: 12084532
    12. We propose that TIP39 is an endogenous ligand of the PTH2R and that they form a neuromodulator system, which is optimally positioned to regulate limbic, endocrine, and auditory brain functions. PMID: 17394159
    13. TIP39 is essential for germ cell development and may act as an autocrine or paracrine agent within the gonads. PMID: 18483145
    14. Current data support the hypothesis that TIP39 modulates anxiety-related behaviors following environmental provocation. PMID: 18700839

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Parathyroid hormone family
  • 組織特異性：
    Expressed in testis and, less abundantly, in liver and kidney. Expressed in seminiferous tubuli and several brain regions, including nucleus ruber, caudal paralemniscal nucleus, nucleus centralis pontis, and nucleus subparafascicularis thalami. Expressed
  • 數據庫鏈接：


主站蜘蛛池模板： 久久婷婷五月综合97色直播| 欧洲国产伦久久久久久久| 亚洲日韩av一区二区三区四区| 无遮挡十八禁污污网站免费| 久久久无码精品午夜| 少妇和邻居做不戴套视频| 在线 | 国产精品星空传媒丿| 色老板精品视频在线观看| 久久久www成人免费精品| 免费毛片手机在线播放| 樱花草在线社区www中国| 亚洲精品久久久久中文字幕| 久久久亚洲欧洲日产国产成人无码| 综合激情丁香久久狠狠| 久久久久99精品成人品| √天堂资源在线中文8在线最新版| 一品二品三品中文字幕| 西西人体大胆瓣开下部毛茸茸 | 精品人妻无码区在线视频| 午夜视频在线在免费| 国语少妇高潮对白在线| 天天爱天天做狠狠久久做| 无码一区二区三区中文字幕| 国产美女裸体丝袜喷水视频| 国产作爱激烈叫床视频| 国产激情з∠视频一区二区| 性色欲情网站iwww| 巨熟乳波霸若妻在线播放| 狠狠色噜噜狠狠狠狠五月婷| 色两性网欧美| 3344永久在线观看视频| 亚洲国产制服丝袜高清在线| 四虎影库在线永久影院免费观看| 久久国产劲暴∨内射新川| 日本黄漫动漫在线观看视频| 内射合集对白在线| 妺妺窝人体色www在线小说| 久久国产热精品波多野结衣av| 人狥杂交一区欧美二区| 国产suv精品一区二区33| 少妇又爽又刺激视频|