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  4. Recombinant Mouse Translation initiation factor eIF-2B subunit alpha (Eif2b1)

Recombinant Mouse Translation initiation factor eIF-2B subunit alpha (Eif2b1)

  • 中文名稱：
    小鼠Eif2b1重組蛋白
  • 貨號：
    CSB-YP858139MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Eif2b1重組蛋白
  • 貨號：
    CSB-EP858139MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Eif2b1重組蛋白
  • 貨號：
    CSB-EP858139MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Eif2b1重組蛋白
  • 貨號：
    CSB-BP858139MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Eif2b1重組蛋白
  • 貨號：
    CSB-MP858139MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Eif2b1
  • Uniprot No.：
  • 別名：
    Eif2b1Translation initiation factor eIF-2B subunit alpha; eIF-2B GDP-GTP exchange factor subunit alpha
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-305
  • 氨基酸序列
    MEDGELIEYF KSQMKGDPKM ASAVAAIQTL LEFLKRDKGE TLQGLRANLT YAIKTLCGVD SSVAVSSGGE LFLRFISLTS LEYSDYSKCK KIMIERGELF LRRISLSRNK IANLCHTFIK DGARILTHAY SRVVLRVLEE AVAAKKRFSV YITESQPDLS GKKMAKALSH LNVPVTVVLD AAVGYIMEKA DLVIVGAEGV VENGGIINKI GTNQMAVCAK AQNKPFYVVA ESFKFVRLFP LNQEDVPDKF KYKADTLKSV QTGQDLKEEH PWVDYTSPSL ITLLFTDLGV LTPSAVSDEL IKLYL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
  • 基因功能參考文獻：
    1. These are the first data that mechanistically link eIF2Bepsilon abundance to skeletal myofibre hypertrophy. PMID: 21486778
    2. A point mutation in translation initiation factor eIF2B leads to Vanishing White Matter disease. PMID: 22073122
    3. Inhibition of pancreatic protein synthesis in this model of acute pancreatitis most likely results from inhibition of translation initiation from increased eIF2alpha phosphorylation, reduction of eIF2B activity, and inhibition of eIF4F complex formation. PMID: 12773302
  • 蛋白家族：
    EIF-2B alpha/beta/delta subunits family
  • 數(shù)據(jù)庫鏈接：


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