在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Transcriptional regulator Kaiso (Zbtb33)

Recombinant Mouse Transcriptional regulator Kaiso (Zbtb33)

  • 中文名稱：
    小鼠Zbtb33重組蛋白
  • 貨號：
    CSB-YP806880MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Zbtb33重組蛋白
  • 貨號：
    CSB-EP806880MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Zbtb33重組蛋白
  • 貨號：
    CSB-EP806880MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Zbtb33重組蛋白
  • 貨號：
    CSB-BP806880MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Zbtb33重組蛋白
  • 貨號：
    CSB-MP806880MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Zbtb33
  • Uniprot No.：
  • 別名：
    Zbtb33; Kaiso; Transcriptional regulator Kaiso; Zinc finger and BTB domain-containing protein 33
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-671
  • 氨基酸序列
    MESRKLISAT DIQYSASLLN SLNEQRGHGL FCDVTVIVED RKFRAHRNIL SASSTYFHQL FSVAGQVVEL SFIRAEIFAE ILNYIYSSKV VRVRADLLDE LIKSGQLLGV KFIAELGVPL SQVKSISGTE QDGTAETLPS SSSDKSLDME KSKDEAQDNG ATVMPIITES FSLSAEDNEM KKIIVTDSDD DDDDDVIFCS EILPAKEDLP SNNTATQVQP NPASVAISEV TPCASNNSPP VTNITPTQLP TPVNQATLSQ TQGSEELLVS SASTHLTPNI ILLNQAPLTA PPSASSSLPN HMSSSVNVLV QNQQTPNSAV LTGNKAEEEE EIIDDDDDII SSSPDSAVSN TSLVPQADNS KSTTLDGSLT QKMQIPVLPQ EPPSNSLKIS DVITRNTNDP GLRSKHVMEG QKIITLDTAT EIEGLSTGCK VYANIGEDTY DIVIPVKDDP DGGEAKLDNE LPKTSGSEPP NKRMKVKHDD HYELIVDGRV YYICIVCKRS YVCLTSLRRH FNIHSWEKKY QCRYCDKVFP LAEYRTKHEI HHTGERRYQC LTCGKSFINY QFMSSHIKSV HSQDPSGDSK LYRLHPCKSL QIRQYAYLSN KSSAMPVMKD DAVGYKVDAG KEPPVGTTST PPQNKSTFWE DIFIQQENDS IFKQNVTDGS TEFEFIIPES Y
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). May recruit the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. Contributes to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1.
  • 基因功能參考文獻：
    1. We also demonstrate that Kaiso inhibits Znf131 expression, raising the possibility that Kaiso and Znf131 act to fine-tune target gene expression. Together, our findings implicate Znf131 as a co-regulator of Kaiso-mediated biological processes. PMID: 28882591
    2. Study revealed the involvement of the Zbtb33 gene and, probably, the Kaiso protein in the regulation of locomotion and brain morphology in mice PMID: 26454239
    3. S100A3 is a new target gene of Kaiso in mouse skin PMID: 26065264
    4. ZBTB33 expression may elicit intestinal inflammation by antagonizing p120ctn function. PMID: 24040197
    5. derepressed Bcl6 expression may be responsible for increases in germinal centers cell proliferation and splenomegaly of Kaiso knockout mice. PMID: 24269670
    6. KAISO, similar to SMRT, accelerates the cell cycle and increases fat accumulation upon knockdown, identifying KAISO as an adipogenic repressor that likely modulates the mitotic clonal expansion phase of this process. PMID: 22521691
    7. Znf131 is a transcriptional activator, a less common function of POZ-ZF proteins, that is negatively regulated by its heterodimerization partner Kaiso. PMID: 20303951
    8. These results provide the first experimental evidence that rapsyn is a direct sequence-specific target of Kaiso and delta-catenin. PMID: 15282317
    9. p120-catenin and Kaiso are essential components of a new developmental gene regulatory pathway that controls vertebrate morphogenesis. PMID: 15543138
    10. Kaiso translocates to the nucleus to regulate transcription of genes with diverse roles in cell growth and development PMID: 15564377
    11. Kaiso-null mice showed a delayed onset of intestinal tumorigenesis. PMID: 16354691
    12. Our study suggests that this gene is not implicated in the RTT molecular pathogenesis PMID: 16530985
    13. Human zinc finger protein Kaiso could bind with methylated CpG specifically, only in the assistance of the neighboring flank sequence of the zinc finger domain PMID: 17767857
    14. The function of Mecps in mouse development and in neural stem cell derivation, maintenance, and differentiation, was investigated. PMID: 19177165

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in brain, heart, kidney, liver, lung, neuromuscular junctions, skeletal muscle, spleen and testis.
  • 數據庫鏈接：


主站蜘蛛池模板： 国产suv精二区| 亚洲国产欧美在线成人aaaa| av激情亚洲男人的天堂| 插插插精品亚洲一区| 国产精品亚洲а∨天堂123| 国产成人精品一区二区三区无码| 国产精品午夜无码av天美传媒| 爱做久久久久久| 亚欧成a人无码精品va片| 免费国产午夜理论片不卡| 久久午夜色播影院| 亚洲乱妇亚洲乱妇xinglu| 色插图午夜影院| 性一交一无一伦一精一品| 亚洲国产午夜精华无码福利| 亚洲成在人线在线播放无码vr | 亚洲欧美日韩综合久久久久久| 欧美日韩综合一区二区三区 | 国产偷国产偷亚洲高清app| 在线看免费无码av天堂| 边吃奶边添下面好爽| 日韩精品真人荷官无码| 米奇影院888奇米色99在线| 国产青榴视频在线观看| 2021国产精品自在自线| 五月天激情电影| 日本精品中文字幕在线播放| 亚洲人成网站18禁止大| 老司机午夜福利av无码特黄a| 国产亚洲精品自在久久| 色综合av综合无码综合网站| 中文文字幕文字幕亚洲色| 国内少妇偷人精品视频| 人妻丰满熟妇岳av无码区hd | 久久久噜噜噜www成人网| 妺妺窝人体色www看美女| 青春草在线视频免费观看| 国产如狼似虎富婆找强壮黑人| 少妇人妻无码专区在线视频 | 亚洲理论电影在线观看| 国产午夜精品无码|