在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Thyrotropin-releasing hormone receptor (Trhr), partial

Recombinant Mouse Thyrotropin-releasing hormone receptor (Trhr), partial

  • 中文名稱：
    小鼠Trhr重組蛋白
  • 貨號：
    CSB-YP024441MO1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Trhr重組蛋白
  • 貨號：
    CSB-EP024441MO1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Trhr重組蛋白
  • 貨號：
    CSB-EP024441MO1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Trhr重組蛋白
  • 貨號：
    CSB-BP024441MO1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Trhr重組蛋白
  • 貨號：
    CSB-MP024441MO1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Trhr; Thyrotropin-releasing hormone receptor; TRH-R; Thyroliberin receptor
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
  • 基因功能參考文獻：
    1. activating TRH/TRH-R1 signaling seems not to be sufficient for gastric stimulation of acylated ghrelin production PMID: 25490146
    2. The central nervous systems effects of taltirelin are mediated primarily by TRH-R1 and not TRH-R2. PMID: 23303050
    3. We suggest that persistent signaling by TRHRs is exhibited when sufficient levels of agonist/receptor/G-protein complexes are established and maintained and that TRH-R2 forms and maintains these complexes more efficiently than TRH-R1. PMID: 22593547
    4. three distinct and discontinuous regions of the TSHR (aa 246-260 and 277-296 on the TSHR A subunit) and aa 381-385 (on the TSHR B subunit) fold together to form a complex TSH binding pocket. PMID: 12593718
    5. the TSHR may not be similar to other model proteins used to define the concept of central immune tolerance. PMID: 14630711
    6. TRH-R1 has a role in mouse lactation and mice lacking the receptor show signs of central hypothyroidism PMID: 14988432
    7. Thyrotropin-releasing hormone binding induces separation of cytoplasmic ends of TRH receptor type 1 transmembrane helix 5 (TMH5) and TMH6 and a rotation of TMH6 that could promote interactions between G proteins and key residues within the TRH receptor. PMID: 15709754
    8. Beta-arrestin has a role in desensitization and internalization but not phosphorylation of the thyrotropin-releasing hormone receptor, which causes translocation of endogenous GRK2 to the plasma membrane PMID: 16183993
    9. the endogenous TRH system is involved in mood regulation, and this function is carried out through TRH-R1-mediated neural pathways PMID: 17666589
    10. A flexible molecular docking procedure revealed that TRH establishes a direct interaction with W6.48 in TRH-R2 but not in TRH-R1. PMID: 17979196
    11. Direct TRH receptor-mediated excitation of histaminergic tuberomamillary neurons by thyrotropin-releasing hormone demands activation of nonselective cation channels as well as electrogenic sodium/divalent calcium ion exchange. PMID: 19357273

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數據庫鏈接：


主站蜘蛛池模板： 久久99国产精品二区| 久久久久久久女国产乱让韩| 中文字幕人妻无码专区| 综合久久—本道中文字幕| 欧美xxxx做受视频| 成人欧美一区二区三区的电影| 男人添女人下部高潮视频| 国精品人妻无码一区免费视频电影| 久久一日本综合色鬼综合色| 99国产精品久久久久久久日本竹 | av片在线观看| 一本一道波多野结衣av黑人| 仙踪林果冻传媒一区二区| 丁香狠狠色婷婷久久综合| 秋霞av鲁丝片一区二区| 国产精品久久久久久久久动漫 | 97人妻人人做人碰人人爽| 免费无码又爽又刺激高潮软件| 国产成人麻豆亚洲综合精品| 成人艳情一二三区| 成人麻豆日韩在无码视频| 人人婷婷人人澡人人爽| 日韩成人大屁股内射喷水| 久久精品中文字幕无码| 亚洲高清成人aⅴ片| 久久一卡二卡三卡四卡| 无码人妻少妇伦在线电影| 日本强伦片中文字幕免费看| 免费啪视频在线观看视频日本| 无码里番纯肉h在线网站| 日韩av无码一区二区三区不卡| 香蕉久久久久久久av网站| 亚洲vs成人无码人在线观看堂 | 天天摸夜夜添夜夜无码| 国产精品毛片一区二区| 无遮挡午夜男女xx00动态| 天堂资源在线www在线观看| 丁香激情综合久久伊人久久| 粉嫩粉嫩的18在线观看| 欧美亚洲另类自拍丝袜| 1000部夫妻午夜免费|