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  4. Recombinant Mouse Thioesterase superfamily member 5 (Them5)

Recombinant Mouse Thioesterase superfamily member 5 (Them5)

  • 中文名稱：
    小鼠Them5重組蛋白
  • 貨號：
    CSB-YP023496MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Them5重組蛋白
  • 貨號：
    CSB-EP023496MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Them5重組蛋白
  • 貨號：
    CSB-EP023496MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Them5重組蛋白
  • 貨號：
    CSB-BP023496MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Them5重組蛋白
  • 貨號：
    CSB-MP023496MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Them5
  • Uniprot No.：
  • 別名：
    Them5; Acot15; Acyl-coenzyme A thioesterase THEM5; Acyl-CoA thioesterase THEM5; EC 3.1.2.2; Acyl-coenzyme A thioesterase 15; Thioesterase superfamily member 5
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-248
  • 氨基酸序列
    MLRTSFQGVA RLVRHKALYR SPCLLPRVHL ASAFGSSTES LVARFCPEKT DLKDYALPNA SWCSDMLSLY QEFLEKTKSG GWIKLPSFKS NRDHIQGLKL PFGLETASDK QDWRLFTRSI QLEGQGYEYV IFFHPSEKKS VCLFQPGPYL EGAPGFAHGG SLAALMDETY SKTAYLAGEG LFTLSLNIKF KNLIPVGSLA VLDIQVEKIE DQKLYMSCIA QSRDKQTVYA KSSGVFLQLQ LEEQSQEQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleoyl-CoA and other unsaturated long-chain fatty acid-CoA esters. Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function.
  • 基因功能參考文獻：
    1. Loss of Them5 specifically alters the remodeling process of the mitochondrial phospholipid cardiolipin. Them5(-/-) mice show deregulation of lipid metabolism and the development of fatty liver, exacerbated by a high-fat diet. PMID: 22586271
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    THEM4/THEM5 thioesterase family
  • 數據庫鏈接：


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