在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Tensin-like C1 domain-containing phosphatase (Tenc1), partial

Recombinant Mouse Tensin-like C1 domain-containing phosphatase (Tenc1), partial

  • 中文名稱：
    小鼠Tns2重組蛋白
  • 貨號：
    CSB-YP807021MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Tns2重組蛋白
  • 貨號：
    CSB-EP807021MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Tns2重組蛋白
  • 貨號：
    CSB-EP807021MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Tns2重組蛋白
  • 貨號：
    CSB-BP807021MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Tns2重組蛋白
  • 貨號：
    CSB-MP807021MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Tns2
  • Uniprot No.：
  • 別名：
    Tns2; Tenc1; Tensin-2; EC 3.1.3.48; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-like C1 domain-containing phosphatase
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin. In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy. Negatively regulates PI3K-AKT pathway activation.
  • 基因功能參考文獻：
    1. deficiency causes alteration of actin remodeling and morphological changes in podocytes and subsequent proteinuria PMID: 27246398
    2. Data suggest that Tenc1 (tensin2) contributes to the maintenance of glomerular basement membrane (GBM) structures and that the genetic background influences the severity of nephrotic syndrome. PMID: 23988887
    3. DISC1-Tensin2 colocalisation was most clearly observed in the Purkinje cells of the mouse cerebellum. PMID: 23233134
    4. C1-Ten is a novel protein tyrosine phosphatase (PTPase) of IRS-1 that acts as a mediator to reduce IRS-1 under a catabolic condition, resulting in muscle atrophy. C1-Ten preferentially dephosphorylated Y612 of IRS-1, which accelerated IRS-1 degradation. PMID: 23401856
    5. tensin2 gene of the ICGN mouse possessed an 8-nucleotide deletion mutation in exon 18, leading to a frameshift and giving rise to a terminal codon at a premature position. PMID: 16688531
    6. Variant 3 expression enhanced the proliferation rate in culture and in vivo tumorigenicity in nude mice PMID: 17006924
    7. Results suggest that tensin2 is involved in expression and extension of nephrin, while tensin2 deficiency may result in proteinuria, associated with the loss of slit integrity. PMID: 19129671
    8. Three strains of the ICGN/Oa mice could be identified by the tensin2 mutation using PCR analysis. The homozygous tensin2 mutation is necessary for the ICGN/Oa mice to develop proteinuria-induced CKD. PMID: 19288329

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 組織特異性：
    Low expression levels in anabolic skeletal muscles.
  • 數據庫鏈接：


主站蜘蛛池模板： 免费全部高h视频无码| 又黄又爽又无遮挡免费的网站 | 亚洲中文无码av永久伊人| 亚洲国产成人精品无码区蜜柚| 中文字幕日韩人妻无码| 日本免费一区二区三区视频观看 | 野外少妇被弄到喷水在线观看| 成人做爰视频www网站| 亚洲成av人片无码迅雷下载| 丰满人妻一区二区三区免费视频| 国产亚洲精品aaaa片app| 婷婷综合久久中文字幕蜜桃三电影 | 日本亚洲色大成网站www| 两性色午夜视频免费播放 | 久久99er精品国产首页| 中文无码精品一区二区三区| 免费体验区试看120秒| 国产熟妇高潮呻吟喷水| 人妻少妇伦在线麻豆m电影| 在线a毛片免费视频观看| 男女无遮挡xx00动态图120秒| 国产精品夜间视频香蕉| 老司机久久精品最新免费| 国语高潮无遮挡无码免费看| 亚洲综合色视频在线观看| 亚洲国产长腿丝袜av天堂| 免费无码a片一区二三区| 国产超碰人人爽人人做av| 成人国产精品秘片多多| 无码人妻精品中文字幕免费东京热 | 人人妻碰人人免费| 亚洲精品黑牛一区二区三区| 成人毛片一区二区| 亚洲经典国产精华液单品榜| 欧美黑人xxxx性高清版| 抽插丰满内射高潮视频| av狠狠色超碰丁香婷婷综合久久| 日本一丰满一bbw| 两个黑人大战嫩白金发美女| 成年轻人电影www无码| 免费网站看v片在线18禁无码|