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  4. Recombinant Mouse Synaptonemal complex protein 2 (Sycp2), partial

Recombinant Mouse Synaptonemal complex protein 2 (Sycp2), partial

  • 中文名稱：
    小鼠Sycp2重組蛋白
  • 貨號：
    CSB-YP022991MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Sycp2重組蛋白
  • 貨號：
    CSB-EP022991MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Sycp2重組蛋白
  • 貨號：
    CSB-EP022991MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Sycp2重組蛋白
  • 貨號：
    CSB-BP022991MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Sycp2重組蛋白
  • 貨號：
    CSB-MP022991MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Sycp2
  • Uniprot No.：
  • 別名：
    Sycp2; Scp2; Synaptonemal complex protein 2; SCP-2; Synaptonemal complex lateral element protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.
  • 基因功能參考文獻：
    1. Using yeast two-hybrid screening, it discovered the surprising finding that the SYCP2 NTR associates well with the centromere. It was reported that the C-terminal region of mSYCP2 was found to be responsible for the association of SYCP3 and SYCP1 for synaptonemal complex (SC) formation. PMID: 28150150
    2. SYCP2 and SYCP3 proteins function in the specificity of chromatin attachment to the chromosome core PMID: 15237206
    3. SYCP2 are not required for centromere cohesion at the metaphase-I stage in male germ cells. PMID: 15870106
    4. SYCP2 is a primary determinant of axial elements and lateral elements and, thus, is required for the incorporation of SYCP3 into synaptonemal complexes. PMID: 16717126
    5. SYCP2 is a primary determinant of axial/lateral elements (AEs/LEs) and is required for the incorporation of SYCP3 into synaptonemal complexes. PMID: 16717126

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  • 亞細胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    SYCP2 family
  • 組織特異性：
    Detected in testis and spermatocytes (at protein level).
  • 數據庫鏈接：


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