Recombinant Mouse Synapse differentiation-inducing gene protein 1 (Syndig1), partial

中文名稱：

小鼠Syndig1重組蛋白
貨號：

CSB-YP382370MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Syndig1重組蛋白
貨號：

CSB-EP382370MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Syndig1重組蛋白
貨號：

CSB-EP382370MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Syndig1重組蛋白
貨號：

CSB-BP382370MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Syndig1重組蛋白
貨號：

CSB-MP382370MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Syndig1
Uniprot No.：

A2ANU3
別名：

Syndig1; Tmem90b; Synapse differentiation-inducing gene protein 1; SynDIG1; Dispanin subfamily C member 2; DSPC2; Transmembrane protein 90B
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation.
基因功能參考文獻：
1. Mice with reduced SynDIG1 exhibit deficits in the structure and function of excitatory synapses. Mature synapses are still present, albeit at a significantly reduced number, suggesting that synapses can reach maturity without SynDIG1. However, the overall reduction in the number of mature synapses by multiple criteria suggests that SynDIG1 is important for normal development. PMID: 27800545
2. This study provides mechanistic insight into SynDIG1 structure and function to demonstrate that its stability and subcellular localization are regulated by activity-dependent palmitoylation PMID: 27445135
亞細胞定位：

Cell membrane; Single-pass type II membrane protein. Early endosome membrane; Single-pass type II membrane protein. Cell junction, synapse, postsynaptic density membrane. Cell junction, synapse. Cell projection, dendrite. Cell projection, dendritic spine. Note=Shuttles between the cell surface and early endosome membrane.
蛋白家族：

CD225/Dispanin family
組織特異性：

Brain-specific. Expressed in Purkinje neurons in cerebellum. Also detected in the hippocampus. Found at excitatory synapses and postsynaptic cells.
數據庫鏈接：

KEGG: mmu:433485

STRING: 10090.ENSMUSP00000105560

UniGene: Mm.330649